SCHEMBL4044931

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4043376	0.92	CTSK (0.56)	CTSKGPR132CHRNB2CHRNA4CTSS
	SCHEMBL4046339	0.92	CTSK (0.55)	CTSKGPR132CHRNB2CHRNA7CHRNA4
	SCHEMBL4046945	0.89	CTSK (0.55)	CTSKCHRNB2CHRNA7CHRNA4CTSS
	SCHEMBL4039388	0.89	CTSK (0.45)	CTSKGPR132CHRNB2CHRNA7CHRNA4
	SCHEMBL4041333	0.89	CTSK (0.69)	CTSKCTSSGAAACEMAPT
	SCHEMBL4046323	0.88	CTSK (0.54)	CTSKGPR132CTSSGAAACE
	SCHEMBL4037811	0.88	CTSK (0.57)	CTSKGPR132CTSSGAAACE
	SCHEMBL4049108	0.88	CTSK (0.57)	CTSKGPR132CTSSGAAACE
	SCHEMBL4044253	0.87	CTSK (0.48)	CTSKGPR132CHRNB2CHRNA7CHRNA4
	SCHEMBL4044071	0.86	CTSK (0.54)	CTSKCHRNA7CTSSGAAACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.