SCHEMBL4045138

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4039168	0.93	CTSK (0.43)	CTSKNPC1RAB9ASMN1; SMN2PREP
	SCHEMBL4040693	0.92	CTSK (0.44)	CTSKPREPFAPCCR1MC4R
	SCHEMBL4040788	0.92	CTSK (0.51)	CTSKNPC1RAB9ASMN1; SMN2CCR1
	SCHEMBL4043290	0.92	CTSK (0.42)	CTSKPREPFAPCCR1MC4R
	SCHEMBL4045351	0.91	CTSK (0.44)	CTSKSMN1; SMN2PREPFAPCCR1
	SCHEMBL4041623	0.90	CTSK (0.43)	CTSKNPC1RAB9ASMN1; SMN2PREP
	SCHEMBL4042221	0.90	CTSK (0.46)	CTSKPREPFAPCCR1MC4R
	SCHEMBL4039917	0.89	CTSK (0.45)	CTSKPREPFAPCCR1MC4R
	SCHEMBL4043416	0.89	CTSK (0.54)	CTSKSMN1; SMN2PREPFAPCCR1
	SCHEMBL4041462	0.89	CTSK (0.54)	CTSKPREPFAPCCR1MC4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.