Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2172192 | 0.84 | CYP19A1 (0.59) | CYP19A1KMT2AMEN1GAAPOLB | |
| SCHEMBL3321085 | 0.80 | KMT2A (0.53) | KMT2AMEN1POLBKDM4EALDH1A1 | |
| SCHEMBL27799067 | 0.79 | BRD4 (0.44) | CYP19A1BRD4KMT2AMEN1GAA | |
| SCHEMBL5725662 | 0.77 | PPARA (0.54) | KMT2APOLBKDM4ETSHRRECQL | |
| SCHEMBL7556647 | 0.76 | SMN1; SMN2 (0.50) | CYP19A1KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL4043640 | 0.75 | ALDH1A1 (0.51) | POLBKDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL27811793 | 0.75 | CYP19A1 (0.51) | CYP19A1BRD4KMT2APOLBKDM4E | |
| SCHEMBL13462548 | 0.75 | CYP19A1 (0.51) | CYP19A1BRD4KMT2APOLBKDM4E | |
| SCHEMBL8265344 | 0.75 | CYP19A1 (0.56) | CYP19A1BRD4KMT2AMEN1POLB | |
| SCHEMBL1542377 | 0.73 | CYP19A1 (0.61) | CYP19A1BRD4KMT2APOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2020404-A1 | Cyanomethyl substituted N-Acyl Tryptamines | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-02-04 | — | — | EP | disclosed |