Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL660541 | 0.84 | MMP13 (0.70) | ALDH1A1HTTSMN1; SMN2MMP13MTNR1A | |
| Hydrochloric Acid SCHEMBL29194804 | 0.83 | MMP13 (0.68) | ALDH1A1HTTSMN1; SMN2MMP13MTNR1A | |
| SCHEMBL12968963 | 0.81 | ROCK2 (0.60) | ALDH1A1HTTSMN1; SMN2MMP13MTNR1A | |
| SCHEMBL1899410 | 0.81 | NPSR1 (0.57) | ALDH1A1HPGDKDM4ERAB9APOLB | |
| SCHEMBL3323011 | 0.80 | KMT2A (0.56) | ALDH1A1SMN1; SMN2HPGDRAB9APOLB | |
| SCHEMBL16590393 | 0.80 | MMP13 (0.54) | ALDH1A1HTTSMN1; SMN2MMP13MTNR1A | |
| SCHEMBL5724446 | 0.79 | MAPK14 (0.63) | MMP13 | |
| SCHEMBL15834330 | 0.78 | MTNR1A (0.56) | ALDH1A1HTTSMN1; SMN2MMP13MTNR1A | |
| SCHEMBL8646446 | 0.77 | HDAC1 (0.57) | ALDH1A1MMP13RAB9APOLB | |
| SCHEMBL5681744 | 0.76 | PTPN1 (0.56) | ALDH1A1HTTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2020404-A1 | Cyanomethyl substituted N-Acyl Tryptamines | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-02-04 | — | — | EP | disclosed |
| EP-1964834-A1 | Sulphonyltryptophanols | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-09-03 | — | — | EP | disclosed |