Urethane

Urethane

SCHEMBL40457

CCOC(N)=O.O=C(O)O

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Urethane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.88
ALDH1A1 P00352 5/20 0.50
LMNA P02545 4/20 0.48
HSD17B10 Q99714 2/20 0.48
GAA P10253 3/20 0.46
MGAM O43451 1/20 0.46
SI P14410 1/20 0.46
MGAM2 Q2M2H8 1/20 0.46
SOAT1 P35610 1/20 0.46
CHRM2 P08172 2/20 0.42
CHRM4 P08173 2/20 0.42
CHRM5 P08912 2/20 0.42
CHRM1 P11229 2/20 0.42
CHRM3 P20309 2/20 0.42
CHRNB2 P17787 2/20 0.42
CHRNA4 P43681 2/20 0.42
HTR1A P08908 1/20 0.42
TSHR P16473 1/20 0.42
CYP2C19 P33261 1/20 0.42
CHRNA7 P36544 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Urethane SCHEMBL4556053 1.00 ALOX15 (0.88) ALOX15ALDH1A1LMNAHSD17B10GAA
Urethane SCHEMBL5458436 0.97 ALOX15 (0.83) ALOX15ALDH1A1LMNAHSD17B10GAA
Urethane SCHEMBL722008 0.97 ALOX15 (0.83) ALOX15ALDH1A1LMNAHSD17B10GAA
Urethane SCHEMBL12983702 0.97 ALOX15 (0.83) ALOX15ALDH1A1LMNAHSD17B10GAA
Urethane SCHEMBL3267746 0.97 ALOX15 (0.83) ALOX15ALDH1A1LMNAHSD17B10GAA
Urethane SCHEMBL27766653 0.97
Urethane SCHEMBL154279 0.94 ALOX15 (0.88) ALOX15ALDH1A1LMNAHSD17B10GAA
Urethane SCHEMBL367439 0.94 ALOX15 (1.00) ALOX15ALDH1A1LMNAHSD17B10GAA
Urethane SCHEMBL8136 0.94
Urethane SCHEMBL8129017 0.94 ALOX15 (1.00) ALOX15ALDH1A1LMNAHSD17B10GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3794 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4638559-A1 ISOCYANATE-FREE AND BPA-FREE CO-POLY(URETHANE-CARBONATE) Cyclicor AB (SE) 2025-10-29 EP claimed
US-12409642-B2 Tungsten oxide nanostructure thin films for electrochromic devices SMART WINDOW INC., LIMITED (HK) 2025-09-09 US claimed
CN-119855872-A Additive for recycling thermosetting material, recyclable thermosetting composition and application thereof 木星产业株式会社 2025-04-18 CN claimed
EP-4400166-A2 METHODS FOR IMPLANTING AND REVERSING STIMULI-RESPONSIVE IMPLANTS Contraline, Inc. (US) 2024-07-17 EP claimed
US-12036134-B2 Engineered sterile cartilage implant plug(s) with sterile, specific instrument kit(s) IN2BONES USA, LLC (US) 2024-07-16 US claimed
WO-2024136735-A1 ISOCYANATE-FREE AND BPA-FREE CO-POLY(URETHANE-CARBONATE) CYCLICOR AB (SE) 2024-06-27 WO claimed
WO-2024115653-A1 COMPRESSIBLE ROTOR ABIOMED EUROPE GMBH (DE) 2024-06-06 WO claimed
US-20240180719-A1 ENGINEERED STERILE CARTILAGE IMPLANT PLUG(S) WITH STERILE, SPECIFIC INSTRUMENT KIT(S) IN2BONES USA, LLC (US) 2024-06-06 US claimed
WO-2024100177-A1 IMPLANTABLE ARTIFICIAL LIGAMENT, AND PROCESS FOR MANUFACTURING SUCH AN ARTIFICIAL LIGAMENT COUSIN BIOTECH (FR) 2024-05-16 WO claimed
CN-113874211-B Transparent conductive polyester film and use thereof 东洋纺株式会社 2024-05-10 CN claimed
WO-2001017575-A1 GRAFT POLYMERIZATION OF SUBSTRATE SURFACES STS BIOPOLYMERS, INC. (US) 2001-03-15 WO claimed
US-5726242-A POLYCARBONATEURETHANE, LOW TEMPERATURE LAMINATION OF COMPLEX SHAPES SUNSTAR GIKEN KABUSHIKI KAISHA (JP) 1998-03-10 US claimed
EP-0349313-B1 Polyurethane polyamide self-crimping conjugate fiber TORAY INDUSTRIES (JP) 1996-04-10 EP claimed
EP-0702071-A2 Two-pack aqueous adhesive SUNSTAR GIKEN KABUSHIKI KAISHA (JP) 1996-03-20 EP claimed
US-5164262-A Hosiery TORAY INDUSTRIES, INC. (JP) 1992-11-17 US claimed
US-5089331-A With desalted carbon black, abrasive, ferromagnetic powder; storage stability FUJI PHOTO FILM CO., LTD. (JP) 1992-02-18 US claimed
US-4970108-A IMPACT STRENGTH BAYER AKTIENGESELLSCHAFT (DE) 1990-11-13 US claimed
EP-0349313-A2 Polyurethane polyamide self-crimping conjugate fiber TORAY INDUSTRIES, INC. (JP) 1990-01-03 EP claimed
US-4696998-A Cyclic heterocarbonates and methods for their preparation and use GENERAL ELECTRIC COMPANY (US) 1987-09-29 US claimed
EP-0007265-B1 UNSATURATED POLYCARBONATE-URETHANES UTILIZABLE IN PHOTORETICULATION COMPOSITIONS; FILM OBTAINED FROM SUCH A COMPOSITION SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) 1982-04-14 EP claimed