Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Urethane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urethane SCHEMBL40457 | 0.97 | ALOX15 (0.88) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| Urethane SCHEMBL4556053 | 0.97 | ALOX15 (0.88) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| Urethane SCHEMBL5458436 | 0.94 | ALOX15 (0.83) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| Urethane SCHEMBL28067104 | 0.94 | ALOX15 (0.83) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| Urethane SCHEMBL12983702 | 0.94 | ALOX15 (0.83) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| Urethane SCHEMBL3267746 | 0.94 | ALOX15 (0.83) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| Urethane SCHEMBL2937457 | 0.94 | — | — | |
| Urethane SCHEMBL27766653 | 0.94 | — | — | |
| Urethane SCHEMBL539516 | 0.94 | ALOX15 (0.94) | ALOX15ALDH1A1LMNAHSD17B10GAA | |
| Urethane SCHEMBL10401061 | 0.92 | ALOX15 (0.88) | ALOX15ALDH1A1LMNAHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3825350-A1 | COMPOSITES WITH REDUCED WEIGHT AND IMPROVED INTERFACIAL STRENGTH | SHPP Global Technologies B.V. (NL) | 2021-05-26 | — | — | EP | claimed |
| WO-2016034615-A1 | AQUEOUS INSECTICIDE FORMULATION CONTAINING HYPERBRANCHED POLYMER | BASF Agro B.V. (NL) | 2016-03-10 | — | — | WO | claimed |
| WO-2021115916-A1 | SUSPENSION CONCENTRATE | BASF Agro B.V. (NL) | 2021-06-17 | — | — | WO | disclosed |
| EP-3825350-A1 | COMPOSITES WITH REDUCED WEIGHT AND IMPROVED INTERFACIAL STRENGTH | SHPP Global Technologies B.V. (NL) | 2021-05-26 | — | — | EP | disclosed |
| EP-3825351-A1 | COMPOSITES WITH IMPROVED ADHESION AND MECHANICAL PERFORMANCE | SABIC Global Technologies B.V. (NL) | 2021-05-26 | — | — | EP | disclosed |
| US-10785973-B2 | Aqueous pesticide microemulsion | BASF SE (DE) | 2020-09-29 | — | — | US | disclosed |
| US-10316131-B2 | Hyperbranched polymer modified with isocyanate linker and mix of short and long chain alkyl polyether | BASF SE (DE) | 2019-06-11 | — | — | US | disclosed |
| EP-3237498-B1 | HYPERBRANCHED POLYMER MODIFIED WITH ISOCYANATE LINKER AND MIX OF SHORT AND LONG CHAIN ALKYL POLYETHER | BASF SE (DE) | 2019-02-20 | — | — | EP | disclosed |
| EP-3188597-B1 | AQUEOUS PESTICIDE MICROEMULSION | BASF SE (DE) | 2019-02-06 | — | — | EP | disclosed |
| US-20170327621-A1 | HYPERBRANCHED POLYMER MODIFIED WITH ISOCYANATE LINKER AND MIX OF SHORT AND LONG CHAIN ALKYL POLYETHER | BASF SE (DE) | 2017-11-16 | — | — | US | disclosed |
| EP-3237498-A1 | HYPERBRANCHED POLYMER MODIFIED WITH ISOCYANATE LINKER AND MIX OF SHORT AND LONG CHAIN ALKYL POLYETHER | BASF SE (DE) | 2017-11-01 | — | — | EP | disclosed |
| US-9801372-B2 | Polymers for increasing the soil mobility of low-solubility insecticides | BASF SE (DE) | 2017-10-31 | — | — | US | disclosed |
| US-20170280710-A1 | AQUEOUS PESTICIDE MICROEMULSION | BASF SE (DE) | 2017-10-05 | — | — | US | disclosed |
| EP-3188597-A1 | AQUEOUS PESTICIDE MICROEMULSION | BASF SE (DE) | 2017-07-12 | — | — | EP | disclosed |
| WO-2016102203-A1 | HYPERBRANCHED POLYMER MODIFIED WITH ISOCYANATE LINKER AND MIX OF SHORT AND LONG CHAIN ALKYL POLYETHER | BASF SE (DE) | 2016-06-30 | — | — | WO | disclosed |
| WO-2016034615-A1 | AQUEOUS INSECTICIDE FORMULATION CONTAINING HYPERBRANCHED POLYMER | BASF Agro B.V. (NL) | 2016-03-10 | — | — | WO | disclosed |
| WO-2016034618-A1 | AQUEOUS PESTICIDE MICROEMULSION | BASF SE (DE) | 2016-03-10 | — | — | WO | disclosed |
| US-20120053221-A1 | Polymers for Increasing the Soil Mobility of Low-Solubility Insecticides | BASF SE (DE) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10316131-B2 | Hyperbranched polymer modified with isocyanate linker and mix of short and long chain alkyl polyether | ATL3, HACD3, GHDC | ALOX15 3638/4885ALDH1A1 3533/4885LMNA 2887/4885 |
| US-20170280710-A1 | AQUEOUS PESTICIDE MICROEMULSION | PLD1, CHRM2, PLD2 | ALOX15 194/4885ALDH1A1 2051/4885LMNA 152/4885 |
| US-10785973-B2 | Aqueous pesticide microemulsion | PLD1, CHRM2, PLD2 | ALOX15 194/4885ALDH1A1 2051/4885LMNA 152/4885 |
| US-20120053221-A1 | Polymers for Increasing the Soil Mobility of Low-Solubility Insecticides | SMARCA1, PWWP2B, SMARCB1 | ALOX15 2348/4885ALDH1A1 2892/4885LMNA 2976/4885 |
| US-20170327621-A1 | HYPERBRANCHED POLYMER MODIFIED WITH ISOCYANATE LINKER AND MIX OF SHORT AND LONG CHAIN ALKYL POLYETHER | ATL3, HACD3, GHDC | ALOX15 3638/4885ALDH1A1 3533/4885LMNA 2887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.