Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ1 | P51787 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4045505 | 0.93 | KCNQ1 (0.38) | KCNQ1HSD17B10CTSKELOVL6HCRTR2 | |
| SCHEMBL4043490 | 0.92 | CTSK (0.40) | KCNQ1HSD17B10CTSKELOVL6HCRTR2 | |
| SCHEMBL4047237 | 0.90 | SMYD3 (0.35) | CTSKSMYD3TSHRALDH1A1 | |
| SCHEMBL4045044 | 0.90 | CTSK (0.36) | CTSKELANE | |
| SCHEMBL4046543 | 0.89 | KCNQ1 (0.38) | KCNQ1HSD17B10ELOVL6HCRTR2HPGD | |
| SCHEMBL4045409 | 0.88 | CTSK (0.35) | CTSK | |
| SCHEMBL4040745 | 0.87 | HSD17B10 (0.36) | KCNQ1HSD17B10CTSKELOVL6HCRTR2 | |
| SCHEMBL4051200 | 0.86 | CTSK (0.44) | CTSK | |
| SCHEMBL4052140 | 0.85 | HSD17B10 (0.36) | KCNQ1HSD17B10CTSKHCRTR2SMYD3 | |
| SCHEMBL4048509 | 0.84 | CTSK (0.38) | CTSKALDH1A1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |