Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ1 | P51787 | 1/20 | 0.38 |
| ▸ | CTSV | O60911 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | GCK | P35557 | 2/20 | 0.33 |
| ▸ | F12 | P00748 | 2/20 | 0.33 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.32 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4051046 | 0.90 | CTSV (0.39) | CTSVCTSLCTSSF12GPR132 | |
| SCHEMBL4045926 | 0.90 | GPR132 (0.36) | CTSVCTSLCTSSGCKGPR132 | |
| SCHEMBL4043490 | 0.90 | CTSK (0.40) | KCNQ1CTSLCTSSHSD17B10HCRTR2 | |
| SCHEMBL4046102 | 0.89 | KCNQ1 (0.38) | KCNQ1HSD17B10HPGDHCRTR2ELOVL6 | |
| SCHEMBL4045505 | 0.89 | KCNQ1 (0.38) | KCNQ1HSD17B10HCRTR2ELOVL6 | |
| SCHEMBL4043817 | 0.88 | CTSL (0.39) | KCNQ1CTSVCTSLCTSSF12 | |
| SCHEMBL4042447 | 0.87 | CTSL (0.43) | CTSVCTSLCTSSGCK | |
| SCHEMBL4043670 | 0.85 | CTSV (0.37) | KCNQ1CTSVCTSLCTSSGCK | |
| SCHEMBL4041667 | 0.85 | HTRA1 (0.38) | CTSVCTSLCTSSF12GPR132 | |
| SCHEMBL4041994 | 0.84 | CTSS (0.39) | CTSVCTSLCTSSGCKF12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |