Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 3/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4044546 | 0.90 | CTSK (0.39) | CTSKCTSBCTSS | |
| SCHEMBL4048681 | 0.90 | CTSL (0.32) | USP30CTSKCTSS | |
| SCHEMBL4040568 | 0.90 | CTSK (0.36) | CTSKCTSBCTSS | |
| SCHEMBL4044612 | 0.90 | PREP (0.33) | CTSK | |
| SCHEMBL4040702 | 0.89 | CTSK (0.38) | USP30CTSKCTSBCTSS | |
| SCHEMBL4043912 | 0.89 | CTSK (0.32) | USP30CTSKCTSBCTSS | |
| SCHEMBL4052028 | 0.88 | CTSK (0.32) | CTSK | |
| SCHEMBL4039560 | 0.85 | HCRTR2 (0.33) | CTSKCTSBCTSS | |
| SCHEMBL4046790 | 0.83 | USP30 (0.36) | USP30CTSKCTSBCTSS | |
| SCHEMBL4045954 | 0.83 | SMYD3 (0.33) | CTSKCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010523-A1 | SPIROCOMPOUNDS USEFUL AS MODULATORS FOR DOPAMINE D3 RECEPTORS | GLAXO GROUP LIMITED (GB) | 2009-01-07 | — | — | EP | claimed |
| WO-2007125061-A1 | SPIROCOMPOUNDS USEFUL AS MODULATORS FOR DOPAMINE D3 RECEPTORS | GLAXO GROUP LIMITED (GB) | 2007-11-08 | — | — | WO | claimed |