Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.32 |
| ▸ | MC4R | P32245 | 1/20 | 0.31 |
| ▸ | MC5R | P33032 | 1/20 | 0.31 |
| ▸ | MC3R | P41968 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4044672 | 0.91 | CTSV (0.33) | CTSK | |
| SCHEMBL4047331 | 0.91 | CTSK (0.40) | CTSK | |
| SCHEMBL4039560 | 0.91 | HCRTR2 (0.33) | CTSKSMN1; SMN2 | |
| SCHEMBL4042699 | 0.90 | CTSK (0.32) | CTSK | |
| SCHEMBL4045954 | 0.89 | SMYD3 (0.33) | CTSKALDH1A1MAPT | |
| SCHEMBL4047167 | 0.88 | USP30 (0.36) | CTSK | |
| SCHEMBL4040568 | 0.85 | CTSK (0.36) | CTSK | |
| SCHEMBL4043944 | 0.84 | CTSK (0.33) | CTSKALDH1A1 | |
| SCHEMBL4043912 | 0.83 | CTSK (0.32) | CTSKMAPTPKM | |
| SCHEMBL4042344 | 0.83 | CTSK (0.33) | CTSKMC4RMC5RMC3RALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |