Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.35 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.35 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | KDM6B | O15054 | 1/20 | 0.30 |
| ▸ | KDM5C | P41229 | 1/20 | 0.30 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4047411 | 0.93 | CYP2D6 (0.45) | CYP2D6CYP2C19LMNAEGLN1LDHA | |
| SCHEMBL31613206 | 0.89 | CYP2D6 (0.43) | CYP2D6CYP2C19LMNAEGLN1LDHA | |
| Ethylene SCHEMBL10456946 | 0.84 | KDM4E (0.50) | POLBPRMT1MAPK1KDM4EALDH1A1 | |
| SCHEMBL2240590 | 0.83 | CA3 (0.42) | CYP2D6CYP2C19LMNAEGLN1LDHA | |
| SCHEMBL18886295 | 0.83 | PRMT1 (0.46) | CYP2D6CYP2C19LMNAEGLN1LDHA | |
| SCHEMBL3497556 | 0.80 | — | — | |
| SCHEMBL8958360 | 0.79 | KDM4E (0.43) | CYP2D6CYP2C19POLBPRMT1MAPK1 | |
| SCHEMBL3174690 | 0.79 | KDM4E (0.50) | CYP2D6CYP2C19POLBPRMT1MAPK1 | |
| SCHEMBL6421935 | 0.78 | — | — | |
| SCHEMBL1863794 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972038-A | METAL PHTHALOCYANINE PHOTOBLEACH COMPOUND; DIETHYLENE TRIAMINE PENTAACETATE, DIETHYLENE TRIAMINE PENTA(METHYLENE PHOSPHONATE), AND MIXTURES THEREOF. | THE PROCTER & GAMBLE COMPANY (US) | 1999-10-26 | — | — | US | disclosed |
| WO-1997031994-A1 | CHELANT ENHANCED PHOTOBLEACHING | THE PROCTER & GAMBLE COMPANY (US) | 1997-09-04 | — | — | WO | disclosed |