Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.74 |
| ▸ | PPARG | P37231 | 10/20 | 0.74 |
| ▸ | SRR | Q9GZT4 | 4/20 | 0.73 |
| ▸ | PPARD | Q03181 | 1/20 | 0.66 |
| ▸ | PSAT1 | Q9Y617 | 2/20 | 0.66 |
| ▸ | LTA4H | P09960 | 2/20 | 0.58 |
| ▸ | LAP3 | P28838 | 1/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aminooxyphenylpropionate SCHEMBL6513696 | 0.86 | SRR (1.00) | PPARAPPARGSRRPSAT1 | |
| Aminooxyphenylpropionate SCHEMBL1520985 | 0.86 | SRR (1.00) | PPARAPPARGSRRPSAT1 | |
| Aminooxyphenylpropionate SCHEMBL1401589 | 0.86 | SRR (1.00) | PPARAPPARGSRRPSAT1 | |
| Methylamine SCHEMBL5607297 | 0.86 | PPARA (0.71) | PPARAPPARGSRRPPARDLTA4H | |
| SCHEMBL6713386 | 0.85 | PPARG (1.00) | PPARAPPARG | |
| SCHEMBL5606931 | 0.85 | PPARA (0.74) | PPARAPPARGPPARDLTA4HFFAR1 | |
| Aminooxyphenylpropionate SCHEMBL1357763 | 0.84 | SRR (0.96) | PPARAPPARGSRRPSAT1 | |
| Rubidium SCHEMBL5607457 | 0.84 | PPARA (0.72) | PPARAPPARGPPARDLTA4HFFAR1 | |
| Ammonia Solution, Strong SCHEMBL5606255 | 0.84 | PPARA (0.72) | PPARAPPARGPPARDLTA4HFFAR1 | |
| SCHEMBL5607112 | 0.84 | PPARA (0.72) | PPARAPPARGPPARDLTA4HFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427451-B1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BIOLAB CO LTD (JP) | 2019-03-20 | — | — | EP | disclosed |
| US-20180305373-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | Prism BioLab Co., Ltd. (JP) | 2018-10-25 | — | — | US | disclosed |
| US-10017522-B2 | Alpha helix mimetics and methods relating thereto | Prism BioLab Co., Ltd. (JP) | 2018-07-10 | — | — | US | disclosed |
| US-20150368262-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | Prism BioLab Co., Ltd. (JP) | 2015-12-24 | — | — | US | disclosed |
| US-9040531-B2 | Alpha helix mimetics and methods relating thereto | Prism BioLab Co., Ltd. (JP) | 2015-05-26 | — | — | US | disclosed |
| US-20120088770-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BIOLAB CORPORATION (JP) | 2012-04-12 | — | — | US | disclosed |
| EP-2427451-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BioLab Corporation (JP) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128685-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PRISM BIOLAB CORPORATION (JP) | 2010-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150368262-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PLOD3, COL1A1, THPO | PPARA 766/4885PPARG 773/4885SRR 4610/4885 |
| US-20120088770-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PLOD3, COL1A1, THPO | PPARA 766/4885PPARG 773/4885SRR 4610/4885 |
| US-20180305373-A1 | ALPHA HELIX MIMETICS AND METHODS RELATING THERETO | PLOD3, COL1A1, THPO | PPARA 766/4885PPARG 773/4885SRR 4610/4885 |
| US-10017522-B2 | Alpha helix mimetics and methods relating thereto | PLOD3, COL1A1, THPO | PPARA 766/4885PPARG 773/4885SRR 4610/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.