Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 2/20 | 0.71 |
| ▸ | PDE5A | O76074 | 5/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14122016 | 0.90 | PDE5A (0.67) | CCKBRPDE5AKDM4EHSD17B10TSHR | |
| SCHEMBL14121883 | 0.90 | PDE5A (0.67) | CCKBRPDE5AKDM4EHSD17B10TSHR | |
| SCHEMBL14121446 | 0.90 | PDE5A (0.67) | CCKBRPDE5AKDM4EHSD17B10TSHR | |
| SCHEMBL14122143 | 0.90 | PDE5A (0.67) | CCKBRPDE5AKDM4EHSD17B10TSHR | |
| SCHEMBL5033704 | 0.88 | PDE5A (0.64) | CCKBRPDE5AKDM4EHSD17B10TSHR | |
| SCHEMBL17760585 | 0.88 | CCKBR (0.74) | CCKBRPDE5AKDM4EHSD17B10TSHR | |
| SCHEMBL17760612 | 0.88 | CCKBR (0.74) | CCKBRPDE5AKDM4EHSD17B10TSHR | |
| SCHEMBL17760566 | 0.86 | PDE5A (0.83) | CCKBRPDE5AKDM4EHSD17B10TSHR | |
| SCHEMBL17760547 | 0.86 | PDE5A (0.83) | CCKBRPDE5AKDM4EHSD17B10TSHR | |
| SCHEMBL17760548 | 0.85 | PDE5A (0.69) | CCKBRPDE5AKDM4EHSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009024613-A1 | TETRACYCLIC INDOLOPYRIDINES AS EG5 INHIBITORS | 4SC AG (DE) | 2009-02-26 | — | — | WO | disclosed |