Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4053563 | 0.85 | ITGB3 (0.50) | ITGB3ITGAV | |
| SCHEMBL7556336 | 0.85 | ITGAV (0.40) | ITGB3ITGAV | |
| SCHEMBL7589288 | 0.85 | ITGAV (0.40) | ITGB3ITGAV | |
| SCHEMBL7593066 | 0.85 | ITGAV (0.40) | ITGB3ITGAV | |
| SCHEMBL4370183 | 0.84 | ITGB3 (0.52) | ITGB3ITGAV | |
| SCHEMBL4371975 | 0.84 | ITGB3 (0.41) | ITGB3ITGAV | |
| SCHEMBL4045463 | 0.83 | ITGB3 (0.50) | ITGB3ITGAV | |
| SCHEMBL4374458 | 0.80 | ITGB3 (0.45) | ITGB3ITGAV | |
| SCHEMBL4382525 | 0.80 | ITGB3 (0.46) | ITGB3ITGAV | |
| SCHEMBL4368878 | 0.79 | ITGAV (0.47) | ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1047425-A4 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2009-04-22 | — | — | EP | disclosed |
| EP-1047425-A1 | INTEGRIN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 2000-11-02 | — | — | EP | disclosed |
| WO-1999030709-A1 | INTEGRIN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1999-06-24 | — | — | WO | disclosed |