Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.62 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.61 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.54 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.54 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 2/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.53 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.53 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.53 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.50 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30361159 | 0.92 | HRH3 (0.65) | HRH3ITGB3ITGA2BMEN1KMT2A | |
| SCHEMBL13034092 | 0.87 | L3MBTL3 (0.71) | HRH3ITGB3ITGA2BALOX15L3MBTL3 | |
| SCHEMBL4037902 | 0.86 | L3MBTL3 (0.69) | HRH3ITGB3ITGA2BMEN1KMT2A | |
| SCHEMBL1305974 | 0.85 | USP2 (0.63) | HRH3ITGB3ITGA2BMEN1KMT2A | |
| SCHEMBL6270469 | 0.84 | HRH3 (0.57) | HRH3ITGB3ITGA2BMEN1KMT2A | |
| SCHEMBL4131556 | 0.84 | HRH3 (0.60) | HRH3ITGB3ITGA2BMEN1KMT2A | |
| SCHEMBL13648854 | 0.81 | ALDH1A1 (0.66) | ITGB3ITGA2BMEN1KMT2AALOX15 | |
| Hydrochloric Acid SCHEMBL3967625 | 0.80 | ALDH1A1 (0.64) | ITGB3ITGA2BMEN1KMT2AALOX15 | |
| SCHEMBL4553154 | 0.80 | L3MBTL3 (0.57) | HRH3ITGB3ITGA2BMEN1KMT2A | |
| SCHEMBL1430626 | 0.80 | HRH3 (0.55) | HRH3ITGB3ITGA2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974766-A | N-benzyl-3-phenylamide derivatives, pharmaceutical compositions containing same and uses thereof | 中国药科大学 | 2023-04-18 | — | — | CN | claimed |
| EP-2046796-A1 | TETRAHYDROFURO [3, 2 -B]PYRR0L-3-ONES AS CATHEPSIN K INHIBITORS | Amura Therapeutics Limited (GB) | 2009-04-15 | — | — | EP | claimed |
| WO-2008007114-A1 | TETRAHYDROFURO [3, 2 -B] PYRR0L-3-ONES AS CATHEPSIN K INHIBITORS | AMURA THERAPEUTICS LIMITED (GB) | 2008-01-17 | — | — | WO | claimed |
| CN-115974766-A | N-benzyl-3-phenylamide derivatives, pharmaceutical compositions containing same and uses thereof | 中国药科大学 | 2023-04-18 | — | — | CN | disclosed |
| WO-2008007109-A1 | FURO[3,2-B]PYRROL-3-ONE DERIVATIVES AND THEIR USE AS CYSTEINYL PROTEINASE INHIBITORS | AMURA THERAPEUTICS LIMITED (GB) | 2008-01-17 | — | — | WO | disclosed |