Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.57 |
| ▸ | L3MBTL3 | Q96JM7 | 4/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.56 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.56 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.56 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.48 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.46 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13034092 | 0.88 | L3MBTL3 (0.71) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL1663610 | 0.87 | USP2 (0.60) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL4037902 | 0.87 | L3MBTL3 (0.69) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL21627430 | 0.86 | AOC3 (0.61) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL4048623 | 0.84 | HRH3 (0.62) | HRH3L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL1397706 | 0.84 | GSK3B (0.62) | ALOX15GSK3BMEN1KMT2ACHRNA7 | |
| Bromide SCHEMBL27592745 | 0.82 | GSK3B (0.60) | ALOX15GSK3BMEN1KMT2ACHRNA7 | |
| Hydrochloric Acid SCHEMBL16209943 | 0.82 | GSK3B (0.60) | ALOX15GSK3BMEN1KMT2ACHRNA7 | |
| SCHEMBL19859000 | 0.82 | ALDH1A1 (0.58) | L3MBTL3L3MBTL1MBTD1TP53BP1L3MBTL4 | |
| SCHEMBL30754005 | 0.81 | HRH3 (0.62) | HRH3L3MBTL3L3MBTL1ALOX15JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005097103-A2 | DIABETES AND METABOLIC SYNDROME THERAPY UTILIZING CATHEPSIN B INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2005-10-20 | — | — | WO | disclosed |