SCHEMBL4048734

SCHEMBL4048734

CC(C)(C)COC(=O)N1CCC(COc2cnc(-c3ccc(S(C)(=O)=O)cc3)cn2)CC1

nearest known ligand 0.49

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 20/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4049838 0.91 GPR119 (0.49) GPR119
SCHEMBL4053229 0.87 GPR119 (0.61) GPR119
SCHEMBL4061203 0.86 GRIN2B (0.48) GPR119
SCHEMBL4055470 0.86 GPR119 (0.45) GPR119
SCHEMBL384779 0.85 GPR119 (0.58) GPR119
SCHEMBL4049849 0.84 GPR119 (0.44) GPR119
SCHEMBL4051025 0.84 GPR119 (0.47) GPR119
SCHEMBL4056120 0.84 GPR119 (0.51) GPR119
SCHEMBL4053560 0.84 GPR119 (0.52) GPR119
SCHEMBL4055083 0.81 GPR119 (0.44) GPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009106561-A1 PYRAZINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS BIOVITRUM AB (PUBL) (SE) 2009-09-03 WO disclosed