Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 17/20 | 0.44 |
| ▸ | GPR183 | P32249 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4049838 | 0.88 | GPR119 (0.49) | GPR119GPR183 | |
| SCHEMBL4053229 | 0.84 | GPR119 (0.61) | GPR119GPR183 | |
| SCHEMBL4048734 | 0.84 | GPR119 (0.49) | GPR119 | |
| SCHEMBL4061203 | 0.83 | GRIN2B (0.48) | GPR119CA2PTGS2PTGS1 | |
| SCHEMBL4055470 | 0.83 | GPR119 (0.45) | GPR119GPR183PTGS2PTGS1 | |
| SCHEMBL384779 | 0.82 | GPR119 (0.58) | GPR119 | |
| SCHEMBL4056120 | 0.81 | GPR119 (0.51) | GPR119GPR183PTGS2PTGS1 | |
| SCHEMBL4053560 | 0.81 | GPR119 (0.52) | GPR119GPR183 | |
| SCHEMBL4055083 | 0.79 | GPR119 (0.44) | GPR119GPR183PTGS2PTGS1 | |
| SCHEMBL4059388 | 0.79 | LMNA (0.44) | GPR119GPR183CA2PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106561-A1 | PYRAZINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | disclosed |