Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.33 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.33 |
| ▸ | MYC | P01106 | 2/20 | 0.32 |
| ▸ | MAX | P61244 | 2/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | IDE | P14735 | 1/20 | 0.31 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.30 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4048785 | 1.00 | HTT (0.37) | HTTPIM1MEN1NPC1KMT2A | |
| SCHEMBL4055993 | 0.91 | PTGDR2 (0.36) | HTTPIM1MEN1NPC1KMT2A | |
| SCHEMBL4055996 | 0.91 | PTGDR2 (0.36) | HTTPIM1MEN1NPC1KMT2A | |
| SCHEMBL4052695 | 0.85 | MEN1 (0.34) | MEN1NPC1KMT2ATNNI3TNNT2 | |
| SCHEMBL4052690 | 0.85 | MEN1 (0.34) | MEN1NPC1KMT2ATNNI3TNNT2 | |
| SCHEMBL4050710 | 0.84 | ALOX5 (0.41) | HTTALOX5 | |
| SCHEMBL4050707 | 0.84 | ALOX5 (0.41) | HTTALOX5 | |
| SCHEMBL4059814 | 0.84 | ALOX5 (0.41) | HTTALOX5 | |
| SCHEMBL4059813 | 0.84 | ALOX5 (0.41) | HTTALOX5 | |
| SCHEMBL4053974 | 0.77 | PTPN1 (0.39) | MEN1NPC1KMT2ARAB9AMYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | claimed |
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |