Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.34 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.33 |
| ▸ | MAX | P61244 | 1/20 | 0.33 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.33 |
| ▸ | IDE | P14735 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4055996 | 1.00 | PTGDR2 (0.36) | PTGDR2ALOX5MEN1KMT2ANPC1 | |
| SCHEMBL4048785 | 0.91 | HTT (0.37) | PTGDR2ALOX5MEN1KMT2ANPC1 | |
| SCHEMBL4048783 | 0.91 | HTT (0.37) | PTGDR2ALOX5MEN1KMT2ANPC1 | |
| SCHEMBL4052695 | 0.87 | MEN1 (0.34) | ALOX5MEN1KMT2ANPC1TNNI3 | |
| SCHEMBL4052690 | 0.87 | MEN1 (0.34) | ALOX5MEN1KMT2ANPC1TNNI3 | |
| SCHEMBL4052876 | 0.82 | PTPN1 (0.49) | ALOX5CISD1PTPN1POLB | |
| SCHEMBL4052873 | 0.82 | PTPN1 (0.49) | ALOX5CISD1PTPN1POLB | |
| SCHEMBL4053337 | 0.82 | PTPN1 (0.40) | ALOX5PTGS1PTGS2PTPN1 | |
| SCHEMBL4053340 | 0.82 | PTPN1 (0.40) | ALOX5PTGS1PTGS2PTPN1 | |
| SCHEMBL4060733 | 0.78 | ENPP2 (0.48) | MEN1KMT2ACISD1PTPN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | claimed |
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |