Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.61 |
| ▸ | RXRB | P28702 | 1/20 | 0.61 |
| ▸ | TYR | P14679 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | GCGR | P47871 | 1/20 | 0.48 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4052995 | 1.00 | RXRA (0.61) | RXRARXRBTYRRAB9AALDH1A1 | |
| SCHEMBL4053578 | 0.86 | RAB9A (0.53) | RXRARXRBTYRRAB9AALDH1A1 | |
| SCHEMBL4061167 | 0.86 | RAB9A (0.53) | RXRARXRBTYRRAB9AALDH1A1 | |
| SCHEMBL23223734 | 0.86 | RAB9A (0.69) | RAB9AALDH1A1LMNAMAPTHPGD | |
| SCHEMBL13160063 | 0.86 | RXRA (0.72) | RXRARXRBRAB9AALDH1A1NPC1 | |
| SCHEMBL11614936 | 0.86 | RAB9A (0.69) | RAB9AALDH1A1LMNAMAPTHPGD | |
| SCHEMBL12279053 | 0.86 | RXRA (0.72) | RXRARXRBRAB9AALDH1A1NPC1 | |
| SCHEMBL4048879 | 0.85 | RAB9A (0.50) | RXRARXRBTYRRAB9AALDH1A1 | |
| SCHEMBL4057146 | 0.84 | FFAR1 (0.56) | RXRARXRBRAB9AALDH1A1LMNA | |
| SCHEMBL4055268 | 0.84 | FFAR1 (0.56) | RXRARXRBRAB9AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |