Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.45 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4053578 | 1.00 | RAB9A (0.53) | RAB9ANPC1ALDH1A1LMNAMAPT | |
| SCHEMBL4055268 | 0.87 | FFAR1 (0.56) | RAB9ANPC1ALDH1A1LMNAMAPT | |
| SCHEMBL4057146 | 0.87 | FFAR1 (0.56) | RAB9ANPC1ALDH1A1LMNAMAPT | |
| SCHEMBL4052995 | 0.86 | RXRA (0.61) | RAB9ANPC1ALDH1A1LMNAMAPT | |
| SCHEMBL4048858 | 0.86 | RXRA (0.61) | RAB9ANPC1ALDH1A1LMNAMAPT | |
| SCHEMBL16117358 | 0.85 | NPC1 (0.50) | RAB9ANPC1ALDH1A1SMN1; SMN2HSP90AA1 | |
| SCHEMBL16117356 | 0.85 | NPC1 (0.50) | RAB9ANPC1ALDH1A1SMN1; SMN2HSP90AA1 | |
| SCHEMBL6142721 | 0.83 | ALDH1A3 (0.50) | RAB9ANPC1ALDH1A1LMNAMAPT | |
| SCHEMBL23223734 | 0.82 | RAB9A (0.69) | RAB9ANPC1ALDH1A1LMNAMAPT | |
| SCHEMBL1532117 | 0.82 | TYR (0.61) | ALDH1A1HPGDTSHRALDH1A3TYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |