Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 14/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4054943 | 1.00 | HPGD (0.48) | HPGDALOX5PTPN1MEN1MITF | |
| SCHEMBL4050515 | 0.93 | HPGD (0.48) | HPGDALOX5PTPN1 | |
| SCHEMBL4050517 | 0.93 | HPGD (0.48) | HPGDALOX5PTPN1 | |
| SCHEMBL4052876 | 0.92 | PTPN1 (0.49) | HPGDALOX5PTPN1 | |
| SCHEMBL4052873 | 0.92 | PTPN1 (0.49) | HPGDALOX5PTPN1 | |
| SCHEMBL4058070 | 0.91 | PTPN1 (0.45) | HPGDALOX5PTPN1ALDH1A1MAPT | |
| SCHEMBL4058075 | 0.91 | PTPN1 (0.45) | HPGDALOX5PTPN1ALDH1A1MAPT | |
| SCHEMBL4052918 | 0.91 | ALOX5 (0.52) | HPGDALOX5PTPN1MEN1MITF | |
| SCHEMBL4052922 | 0.91 | ALOX5 (0.52) | HPGDALOX5PTPN1MEN1MITF | |
| SCHEMBL4054034 | 0.91 | ALOX5 (0.46) | HPGDALOX5PTPN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | claimed |
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |