Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10685516 | 0.80 | PPID (0.63) | ALDH1A1KMT2AMAPTLMNAMEN1 | |
| SCHEMBL7428442 | 0.80 | LMNA (0.56) | ALDH1A1KMT2AHPGDMAPTLMNA | |
| SCHEMBL14450265 | 0.79 | MAPT (0.60) | ALDH1A1KMT2AMAPTLMNAMEN1 | |
| SCHEMBL11458148 | 0.79 | MAPT (0.67) | ALDH1A1KMT2AMAPTLMNAMEN1 | |
| SCHEMBL68851 | 0.78 | CYP4Z1 (0.62) | ALDH1A1KMT2AMAPTLMNAMEN1 | |
| SCHEMBL2636023 | 0.77 | MAPT (0.60) | ALDH1A1KMT2AMAPTLMNAMEN1 | |
| SCHEMBL10686887 | 0.77 | MAPT (0.58) | ALDH1A1KMT2AMAPTLMNAMEN1 | |
| SCHEMBL5153509 | 0.77 | USP2 (0.61) | ALDH1A1KMT2AMAPTLMNAMEN1 | |
| SCHEMBL10682388 | 0.77 | TP53 (0.58) | ALDH1A1KMT2AHPGDMAPTLMNA | |
| SCHEMBL31225554 | 0.77 | PPID (0.59) | ALDH1A1KMT2AMAPTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109998-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |
| WO-2009109998-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |