Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5154921 | 0.84 | ALDH1A1 (0.64) | LMNAALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL4049111 | 0.80 | ALDH1A1 (0.63) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5153509 | 0.77 | USP2 (0.61) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4369727 | 0.75 | MAPT (0.72) | LMNAALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL2432662 | 0.75 | HTT (0.50) | LMNAALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL10685516 | 0.75 | PPID (0.63) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5157218 | 0.75 | NPC1 (0.59) | LMNAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11598073 | 0.74 | ALDH1A1 (0.75) | LMNAALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL7760696 | 0.74 | ALDH1A1 (0.75) | LMNAALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL23727265 | 0.74 | EPHX1 (0.65) | LMNAALDH1A1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235793-A2 | VLA-4 INTEGRIN ANTAGONISTS | Novartis AG (CH) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001042192-A2 | VLA-4 INTEGRIN ANTAGONISTS | NOVARTIS AG (CH) | 2001-06-14 | — | — | WO | disclosed |