Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL3820514 | 0.98 | LMNA (0.33) | LMNAHPGD | |
| SCHEMBL6678747 | 0.75 | TDP1 (0.38) | LMNAHPGDALDH1A1HSD17B10TDP1 | |
| SCHEMBL29151144 | 0.74 | TDP1 (0.37) | LMNAHPGDALDH1A1HSD17B10TDP1 | |
| SCHEMBL30389041 | 0.73 | LMNA (0.40) | LMNAHPGDALDH1A1HSD17B10TDP1 | |
| SCHEMBL27143137 | 0.72 | ERN1 (0.31) | — | |
| SCHEMBL30718710 | 0.72 | ERN1 (0.31) | — | |
| SCHEMBL4055774 | 0.72 | — | — | |
| SCHEMBL30453312 | 0.62 | CA1 (0.36) | — | |
| SCHEMBL15332907 | 0.61 | ALDH1A1 (0.33) | HPGDALDH1A1HSD17B10 | |
| SCHEMBL23668349 | 0.61 | ABCG2 (0.37) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1824825-A4 | SUBSTITUTED PYRIDOXINES AS ANTI-PLATELET AGENTS | MEDICURE INT INC (BB) | 2009-07-08 | — | — | EP | disclosed |
| EP-1824825-A1 | SUBSTITUTED PYRIDOXINES AS ANTI-PLATELET AGENTS | Medicure International Inc. (BB) | 2007-08-29 | — | — | EP | disclosed |
| WO-2006045203-A1 | SUBSTITUTED PYRIDOXINES AS ANTI-PLATELET AGENTS | MEDICURE INTERNATIONAL INC. (CA) | 2006-05-04 | — | — | WO | disclosed |