Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.42 |
| ▸ | PREP | P48147 | 2/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 4/20 | 0.33 |
| ▸ | CTSS | P25774 | 4/20 | 0.33 |
| ▸ | CTSB | P07858 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4050322 | 0.92 | CTSK (0.34) | CTSKPREPFAPALDH1A1MAPK1 | |
| SCHEMBL4047331 | 0.89 | CTSK (0.40) | CTSKPREPFAPELANEMMP1 | |
| SCHEMBL4049190 | 0.89 | CTSK (0.40) | CTSKCTSLCTSSCTSB | |
| SCHEMBL4047118 | 0.89 | CTSK (0.41) | CTSKPREPFAPELANEMMP1 | |
| SCHEMBL4041363 | 0.88 | CTSK (0.42) | CTSKPREPFAPELANEMMP1 | |
| SCHEMBL4045331 | 0.88 | CTSK (0.43) | CTSKPREPFAPELANEMMP1 | |
| SCHEMBL4045571 | 0.87 | CTSK (0.46) | CTSKPREPFAPELANEMMP1 | |
| SCHEMBL4043196 | 0.87 | CTSK (0.39) | CTSKALDH1A1CTSLCTSSCTSB | |
| SCHEMBL4047069 | 0.87 | CTSK (0.42) | CTSKPREPFAPELANEMMP1 | |
| SCHEMBL4042672 | 0.87 | CTSK (0.41) | CTSKPREPFAPALDH1A1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-B1 | PYRROLE DERIVATIVES AS INHIBITORS OF CYTEINE PROTEASES | AMURA THERAPEUTICS LTD (GB) | 2009-03-04 | — | — | EP | claimed |