Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.49 |
| ▸ | WDR5 | P61964 | 1/20 | 0.47 |
| ▸ | F10 | P00742 | 2/20 | 0.47 |
| ▸ | F11 | P03951 | 2/20 | 0.47 |
| ▸ | F7 | P08709 | 2/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PTPRC | P08575 | 2/20 | 0.45 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | KMO | O15229 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | PLAT | P00750 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5215160 | 0.86 | BCAT2 (0.61) | BCAT2TTRALDH1A1PTPRCCYP2C8 | |
| SCHEMBL594370 | 0.84 | FOLH1 (0.59) | TTRALDH1A1PTPRCCYP2C8CYP2C9 | |
| Water SCHEMBL28745832 | 0.82 | FOLH1 (0.57) | TTRALDH1A1PTPRCCYP2C8CYP2C9 | |
| SCHEMBL29562805 | 0.82 | TTR (0.52) | TTRALDH1A1PTPRCCYP2C8CYP2C9 | |
| SCHEMBL22729968 | 0.82 | TTR (0.52) | TTRALDH1A1PTPRCCYP2C8CYP2C9 | |
| SCHEMBL27736136 | 0.79 | CYP2C8 (0.71) | TTRALDH1A1CYP2C8CYP2C9KDM4E | |
| SCHEMBL3104353 | 0.79 | KDM4C (0.53) | TTRALDH1A1PTPRCCYP2C8CYP2C9 | |
| SCHEMBL1569116 | 0.79 | EGFR (0.57) | TTRALDH1A1CYP2C8CYP2C9KDM4E | |
| SCHEMBL5248866 | 0.78 | KDM4E (0.48) | ALDH1A1KDM4EPLAUPRSS1PRSS2 | |
| SCHEMBL28791455 | 0.78 | CYP2C8 (0.50) | TTRALDH1A1PTPRCCYP2C8CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1824825-A4 | SUBSTITUTED PYRIDOXINES AS ANTI-PLATELET AGENTS | MEDICURE INT INC (BB) | 2009-07-08 | — | — | EP | disclosed |
| EP-1824825-A1 | SUBSTITUTED PYRIDOXINES AS ANTI-PLATELET AGENTS | Medicure International Inc. (BB) | 2007-08-29 | — | — | EP | disclosed |
| WO-2006045203-A1 | SUBSTITUTED PYRIDOXINES AS ANTI-PLATELET AGENTS | MEDICURE INTERNATIONAL INC. (CA) | 2006-05-04 | — | — | WO | disclosed |