Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 2/20 | 0.39 |
| ▸ | CMKLR1 | Q99788 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | FABP3 | P05413 | 3/20 | 0.35 |
| ▸ | FABP4 | P15090 | 3/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | VCP | P55072 | 2/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1131767 | 1.00 | GCGR (0.39) | GCGRCMKLR1CNR1FFAR1FFAR4 | |
| SCHEMBL1132056 | 0.92 | FAAH (0.37) | GCGRCMKLR1CNR1FFAR1FFAR4 | |
| SCHEMBL1131843 | 0.89 | CMKLR1 (0.40) | CMKLR1CNR1FFAR1FFAR4FABP3 | |
| SCHEMBL1131841 | 0.89 | CMKLR1 (0.40) | CMKLR1CNR1FFAR1FFAR4FABP3 | |
| SCHEMBL1131447 | 0.89 | CMKLR1 (0.37) | GCGRCMKLR1FFAR1FFAR4FABP3 | |
| SCHEMBL1131445 | 0.89 | CMKLR1 (0.37) | GCGRCMKLR1FFAR1FFAR4FABP3 | |
| SCHEMBL1131581 | 0.85 | CNR1 (0.39) | CNR1FFAR1FFAR4SCN9AVCP | |
| SCHEMBL12860235 | 0.85 | CNR1 (0.39) | GCGRCNR1FFAR1FFAR4SCN9A | |
| SCHEMBL12860096 | 0.81 | GCGR (0.36) | GCGRFFAR4FABP3FABP4VCP | |
| SCHEMBL1131983 | 0.81 | FAAH (0.36) | GCGRCMKLR1FFAR1FFAR4FABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663105-A4 | CYCLOALKYL HETEROCYCLES FOR TREATING HEPATITIS C VIRUS | BRISTOL MYERS SQUIBB CO (US) | 2009-04-15 | — | — | EP | disclosed |
| EP-1663105-A2 | CYCLOALKYL HETEROCYCLES FOR TREATING HEPATITIS C VIRUS | Bristol-Myers Squibb Company (US) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005034850-A2 | CYCLOALKYL HETEROCYCLES FOR TREATING HEPATITIS C VIRUS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-04-21 | — | — | WO | disclosed |