Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3012099 | 0.82 | CYP3A4 (0.50) | APPCYP3A4IDO1 | |
| SCHEMBL1535653 | 0.81 | TSHR (0.36) | — | |
| SCHEMBL30423197 | 0.80 | GABRP (0.41) | — | |
| SCHEMBL508700 | 0.80 | CYP11B1 (0.36) | — | |
| SCHEMBL643187 | 0.80 | GABRP (0.41) | — | |
| SCHEMBL5311879 | 0.80 | ALDH1A1 (0.44) | — | |
| SCHEMBL2462510 | 0.80 | CYP11B1 (0.36) | — | |
| SCHEMBL34466654 | 0.80 | ALDH1A1 (0.44) | — | |
| SCHEMBL3426875 | 0.79 | AGXT (0.32) | APPCYP3A4IDO1 | |
| Hydrochloric Acid SCHEMBL4180933 | 0.79 | GABRP (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009103478-A1 | PYRIDONE AND PYRIDAZINONE DERIVATIVES AS MCH ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-08-27 | — | — | WO | disclosed |