Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | PREP | P48147 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3458584 | 0.84 | CYP11B1 (0.35) | CYP11B1GRM2PARP1 | |
| SCHEMBL23540665 | 0.81 | DUT (0.37) | CYP11B1 | |
| SCHEMBL1535653 | 0.81 | TSHR (0.36) | — | |
| SCHEMBL643187 | 0.80 | GABRP (0.41) | ALOX5APFEN1 | |
| SCHEMBL34466654 | 0.80 | ALDH1A1 (0.44) | — | |
| SCHEMBL30423197 | 0.80 | GABRP (0.41) | ALOX5APFEN1 | |
| SCHEMBL4050106 | 0.80 | APP (0.35) | — | |
| SCHEMBL2462510 | 0.80 | CYP11B1 (0.36) | CYP11B1ALOX5APFEN1 | |
| SCHEMBL5311879 | 0.80 | ALDH1A1 (0.44) | — | |
| SCHEMBL481257 | 0.79 | IDO1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4688772-A1 | BIARYL DERIVATIVES AND RELATED USES | Moma Therapeutics, Inc. (US) | 2026-02-11 | — | — | EP | disclosed |
| US-20260015360-A1 | BIARYL DERIVATIVES AND RELATED USES | MOMA THERAPEUTICS, INC. | 2026-01-15 | — | — | US | disclosed |
| CN-119451961-A | Carboxamide derivative with RSK inhibition effect, pharmaceutical composition containing carboxamide derivative and application of carboxamide derivative | 广州科恩泰生物医药科技有限公司 | 2025-02-14 | — | — | CN | disclosed |
| US-20250026758-A1 | MUSCARINIC ACETYLCHOLINE M1 RECEPTOR ANTAGONISTS | CONTINEUM THERAPEUTICS INC (US) | 2025-01-23 | — | — | US | disclosed |
| CN-119112895-A | Muscarinic acetylcholine M1 receptor antagonists | 康蒂内乌姆医疗公司 | 2024-12-13 | — | — | CN | disclosed |
| US-20240389588-A1 | COMPOUNDS AND METHODS FOR TREATING NEMATODE INFECTIONS | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2024-11-28 | — | — | US | disclosed |
| WO-2024211834-A1 | BIARYL DERIVATIVES AND RELATED USES | MOMA THERAPEUTICS, INC. (US) | 2024-10-10 | — | — | WO | disclosed |
| US-12054487-B2 | Muscarinic acetylcholine M1 receptor antagonists | CONTINEUM THERAPEUTICS, INC. (US) | 2024-08-06 | — | — | US | disclosed |
| US-12022832-B2 | Compounds and methods for treating nematode infections | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2024-07-02 | — | — | US | disclosed |
| US-12022832-B2 | Compounds and methods for treating nematode infections | THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) | 2024-07-02 | — | — | US | disclosed |
| US-20020022633-A1 | Inhibitors of prenyl-protein transferase | WILLIAMS THERESA M (US) | 2002-02-21 | — | — | US | disclosed |
| WO-2002002108-A1 | INHIBITORS OF PRENYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 2002-01-10 | — | — | WO | disclosed |
| EP-0539086-B1 | Condensed pyrimidine derivatives and their use as angiotensine II antagonists | AMERICAN HOME PROD (US) | 1997-12-29 | — | — | EP | disclosed |
| US-5498776-A | Substituted pyrrolopyrimidines and pyridopyrimidines useful as angiotensin II antagonists | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-03-12 | — | — | US | disclosed |
| US-5451583-A | Angiotensin inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-09-19 | — | — | US | disclosed |
| WO-1994011365-A1 | SUBSTITUTED BENZIMIDAZOLES AND QUINAZOLINES AS ANTIHYPERTENSIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-05-26 | — | — | WO | disclosed |
| US-5283242-A | Hypotensive agents, cardiotonic agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-02-01 | — | — | US | disclosed |
| US-5256654-A | Substituted pyrrolopyrimidines, azepinopyrimidines and pyridopyrimidines useful as angiotensin II antagonists | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-10-26 | — | — | US | disclosed |
| EP-0539086-A2 | Condensed pyrimidine derivatives and their use as angiotensine II antagonists | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-04-28 | — | — | EP | disclosed |
| US-5149699-A | Substituted pyridopyrimidines useful as antgiotensin II antagonists | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12022832-B2 | Compounds and methods for treating nematode infections | HNMT, NISCH, HRH2 | CYP11B1 469/4885GRM2 2569/4885PARP1 4826/4885 |
| US-20260015360-A1 | BIARYL DERIVATIVES AND RELATED USES | POLB, POLA1, POLN | CYP11B1 77/4885GRM2 3655/4885PARP1 277/4885 |
| US-12054487-B2 | Muscarinic acetylcholine M1 receptor antagonists | CHRM1, CHRM2, CHRM3 | CYP11B1 957/4885GRM2 28/4885PARP1 4092/4885 |
| US-20250026758-A1 | MUSCARINIC ACETYLCHOLINE M1 RECEPTOR ANTAGONISTS | CHRM1, CHRM2, CHRM5 | CYP11B1 970/4885GRM2 28/4885PARP1 3976/4885 |
| US-20020022633-A1 | Inhibitors of prenyl-protein transferase | FNTA, KRAS, FNTB | CYP11B1 1882/4885GRM2 4650/4885PARP1 2497/4885 |
| US-20240389588-A1 | COMPOUNDS AND METHODS FOR TREATING NEMATODE INFECTIONS | HNMT, NISCH, HRH2 | CYP11B1 469/4885GRM2 2569/4885PARP1 4826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.