Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4048956 | 0.86 | CYP19A1 (0.67) | ABCG2ABCB1GAAPOLBMAPT | |
| SCHEMBL16894614 | 0.85 | PTAFR (0.49) | ABCG2ABCB1GAAPOLBMAPT | |
| SCHEMBL10425232 | 0.83 | ABCG2 (0.60) | ABCG2ABCB1GAAPOLBMAPT | |
| SCHEMBL17907269 | 0.81 | MEN1 (0.67) | ABCG2ABCB1GAAPOLBMAPT | |
| SCHEMBL16894660 | 0.78 | ODC1 (0.50) | ABCG2ABCB1GAAPOLBMAPT | |
| SCHEMBL5084379 | 0.77 | PTPN1 (0.51) | GAAPOLBMAPTMEN1PABPC1 | |
| SCHEMBL16894664 | 0.76 | MAOB (0.60) | ABCG2ABCB1MAPTCYP19A1CYP3A4 | |
| SCHEMBL30674790 | 0.75 | MAOB (0.57) | ABCG2ABCB1GAAPOLBMAPT | |
| SCHEMBL4037404 | 0.74 | KDM4E (0.54) | ABCG2ABCB1GAAPOLBMAPT | |
| SCHEMBL28879338 | 0.74 | ABCG2 (0.77) | ABCG2ABCB1GAAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7638554-B2 | Flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents | SRI INTERNATIONAL (US) | 2009-12-29 | — | — | US | disclosed |
| US-7638554-B2 | Flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents | SRI INTERNATIONAL (US) | 2009-12-29 | — | — | US | disclosed |
| EP-1495014-B1 | FLAVANOIDS DERIVATIVES AS CHEMOTHERAPEUTIC, CHEMOPREVENTIVE, AND ANTIANGIOGENIC AGENTS | STANFORD RES INST INT (US) | 2009-07-29 | — | — | EP | disclosed |
| US-7329687-B2 | Flavanoid compounds as chemotherapeutic, chemopreventive, and antiangiogenic agents | SRI INTERNATIONAL (US) | 2008-02-12 | — | — | US | disclosed |
| US-7329687-B2 | Flavanoid compounds as chemotherapeutic, chemopreventive, and antiangiogenic agents | SRI INTERNATIONAL (US) | 2008-02-12 | — | — | US | disclosed |
| US-7329687-B2 | Flavanoid compounds as chemotherapeutic, chemopreventive, and antiangiogenic agents | SRI INTERNATIONAL (US) | 2008-02-12 | — | — | US | disclosed |
| US-20040029914-A1 | Novel flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents | SRI INTERNATIONAL | 2004-02-12 | — | — | US | disclosed |
| US-20030229136-A1 | Novel flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents | SRI INTERNATIONAL | 2003-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040029914-A1 | Novel flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents | FLT1, VEGFA, FLT4 | ABCG2 257/4885ABCB1 903/4885GAA 4692/4885 |
| US-20030229136-A1 | Novel flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents | FLT1, VEGFA, FLT4 | ABCG2 245/4885ABCB1 843/4885GAA 4643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.