Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 6/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | MAX | P61244 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4053526 | 0.92 | PTPN1 (0.39) | PTPN1ALOX5HPGDMYCMAX | |
| SCHEMBL4051990 | 0.92 | PTPN1 (0.39) | PTPN1ALOX5HPGDMYCMAX | |
| SCHEMBL4052876 | 0.91 | PTPN1 (0.49) | PTPN1ALOX5HPGDENPP2AR | |
| SCHEMBL4052873 | 0.91 | PTPN1 (0.49) | PTPN1ALOX5HPGDENPP2AR | |
| SCHEMBL4058028 | 0.91 | CISD1 (0.41) | PTPN1ALOX5HPGDENPP2AR | |
| SCHEMBL4053976 | 0.91 | PTPN1 (0.39) | PTPN1ALOX5HPGDMYCMAX | |
| SCHEMBL4053974 | 0.91 | PTPN1 (0.39) | PTPN1ALOX5HPGDMYCMAX | |
| SCHEMBL4054943 | 0.91 | HPGD (0.48) | PTPN1ALOX5HPGDMEN1KMT2A | |
| SCHEMBL4054941 | 0.91 | HPGD (0.48) | PTPN1ALOX5HPGDMEN1KMT2A | |
| SCHEMBL4050515 | 0.91 | HPGD (0.48) | PTPN1ALOX5HPGDARPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | claimed |
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |