Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4052873 | 1.00 | PTPN1 (0.49) | PTPN1ENPP2ALOX5ARHPGD | |
| SCHEMBL4052918 | 0.92 | ALOX5 (0.52) | PTPN1ENPP2ALOX5ARHPGD | |
| SCHEMBL4050515 | 0.92 | HPGD (0.48) | PTPN1ALOX5ARHPGDMAOB | |
| SCHEMBL4050517 | 0.92 | HPGD (0.48) | PTPN1ALOX5ARHPGDMAOB | |
| SCHEMBL4053340 | 0.92 | PTPN1 (0.40) | PTPN1ENPP2ALOX5HPGD | |
| SCHEMBL4053337 | 0.92 | PTPN1 (0.40) | PTPN1ENPP2ALOX5HPGD | |
| SCHEMBL4054943 | 0.92 | HPGD (0.48) | PTPN1ALOX5HPGD | |
| SCHEMBL4052922 | 0.92 | ALOX5 (0.52) | PTPN1ENPP2ALOX5ARHPGD | |
| SCHEMBL4054941 | 0.92 | HPGD (0.48) | PTPN1ALOX5HPGD | |
| SCHEMBL4054034 | 0.92 | ALOX5 (0.46) | PTPN1ENPP2ALOX5ARHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |