Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.35 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | DUSP26 | Q9BV47 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4050377 | 0.91 | PTPN1 (0.40) | ALOX5ENPP2PTPN1ARHPGD | |
| SCHEMBL4054034 | 0.85 | ALOX5 (0.46) | ALOX5NPC1RAB9AENPP2PTPN1 | |
| SCHEMBL4054032 | 0.85 | ALOX5 (0.46) | ALOX5NPC1RAB9AENPP2PTPN1 | |
| SCHEMBL4053526 | 0.85 | PTPN1 (0.39) | ALOX5PTPN1ARHPGDPOLB | |
| SCHEMBL4051990 | 0.85 | PTPN1 (0.39) | ALOX5PTPN1ARHPGDPOLB | |
| SCHEMBL4052876 | 0.84 | PTPN1 (0.49) | CISD1ALOX5ENPP2PTPN1AR | |
| SCHEMBL4052873 | 0.84 | PTPN1 (0.49) | CISD1ALOX5ENPP2PTPN1AR | |
| SCHEMBL4053974 | 0.84 | PTPN1 (0.39) | ALOX5NPC1RAB9APTPN1AR | |
| SCHEMBL4053976 | 0.84 | PTPN1 (0.39) | ALOX5NPC1RAB9APTPN1AR | |
| SCHEMBL4054943 | 0.84 | HPGD (0.48) | ALOX5RAB9APTPN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | claimed |
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |