Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.55 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.54 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.54 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3837986 | 0.81 | KMT2A (0.41) | GABRA1GABRB2GABRB1GABRA3CLEC4M | |
| SCHEMBL5665566 | 0.81 | GABRA1 (0.54) | GABRA1GABRB2GABRB1GABRA3CLEC4M | |
| SCHEMBL3840520 | 0.81 | CYP1A2 (0.57) | MEN1KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL7504551 | 0.77 | CLEC4M (0.58) | GABRA1GABRB2GABRB1GABRA3CLEC4M | |
| SCHEMBL5664177 | 0.77 | GABRA1 (0.50) | GABRA1GABRB2GABRB1GABRA3CLEC4M | |
| SCHEMBL5246798 | 0.76 | MAPT (0.33) | MEN1KMT2AALDH1A1HSD17B10CYP1A2 | |
| SCHEMBL3976362 | 0.75 | GABRA1 (0.56) | GABRA1GABRB2GABRB1GABRA3CLEC4M | |
| SCHEMBL2970181 | 0.75 | CLEC4M (0.58) | GABRA1GABRB2GABRB1GABRA3CLEC4M | |
| SCHEMBL396948 | 0.74 | CLEC4M (0.56) | GABRA1GABRB2GABRB1GABRA3CLEC4M | |
| SCHEMBL5305475 | 0.73 | GABRA1 (0.59) | GABRA1GABRB2GABRB1GABRA3CLEC4M |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035434-A1 | QUINOLINE DERIVATIVES, THEIR PREPARATION, THEIR USE, AND MEDICAMENTS COMPRISING THEM | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-03-18 | — | — | EP | disclosed |
| US-20080056987-A1 | Quinoline derivatives, their preparation, their use, and medicaments comprising them | BAYER SCHERING PHARMA AG (DE) | 2008-03-06 | — | — | US | disclosed |
| WO-2007147578-A1 | QUINOLINE DERIVATIVES, THEIR PREPARATION, THEIR USE, AND MEDICAMENTS COMPRISING THEM | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-12-27 | — | — | WO | disclosed |
| CN-101087788-A | Quinoline derivative, its use, production and pharmaceutical agents containing the latter | BAYER SCHERING PHARMA AG (DE) | 2007-12-12 | — | — | CN | disclosed |
| US-20060167035-A1 | Quinoline derivative, its use, production and pharmaceutical agents containing the latter | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060167035-A1 | Quinoline derivative, its use, production and pharmaceutical agents containing the latter | NQO2, RECQL, XDH | GABRA1 3070/4885GABRB2 3343/4885GABRB1 3570/4885 |
| US-20080056987-A1 | Quinoline derivatives, their preparation, their use, and medicaments comprising them | RECQL, NQO2, XDH | GABRA1 3229/4885GABRB2 3132/4885GABRB1 3388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.