Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.78 |
| ▸ | MAPT | P10636 | 5/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.78 |
| ▸ | HPGD | P15428 | 2/20 | 0.78 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.77 |
| ▸ | MEN1 | O00255 | 3/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.77 |
| ▸ | NPC1 | O15118 | 2/20 | 0.77 |
| ▸ | RAB9A | P51151 | 1/20 | 0.77 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | CASP1 | P29466 | 1/20 | 0.65 |
| ▸ | CASP7 | P55210 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chrysin Diacetate SCHEMBL15263635 | 0.93 | KDM4E (0.78) | KDM4ECYP3A4MAPTALDH1A1HSD17B10 | |
| Acacetin Diacetate SCHEMBL10026579 | 0.88 | CYP3A4 (1.00) | KDM4ECYP3A4MAPTALDH1A1HSD17B10 | |
| Chrysin Dimethyl Ether SCHEMBL1676012 | 0.87 | ABCG2 (1.00) | KDM4ECYP3A4MAPTALDH1A1HSD17B10 | |
| Chrysin Dimethyl Ether SCHEMBL29403280 | 0.87 | ABCG2 (1.00) | KDM4ECYP3A4MAPTALDH1A1HSD17B10 | |
| SCHEMBL28632938 | 0.85 | CYP3A4 (0.71) | KDM4ECYP3A4MAPTALDH1A1HSD17B10 | |
| SCHEMBL971180 | 0.84 | CREB1 (0.66) | KDM4ECYP3A4MAPTALDH1A1HSD17B10 | |
| Apigenin Triacetate SCHEMBL1676023 | 0.84 | KDM4E (0.88) | KDM4ECYP3A4MAPTALDH1A1HSD17B10 | |
| SCHEMBL972738 | 0.82 | CREB1 (0.70) | KDM4ECYP3A4MAPTALDH1A1HSD17B10 | |
| SCHEMBL974333 | 0.82 | ABCB1 (0.68) | KDM4ECYP3A4MAPTALDH1A1HSD17B10 | |
| Techtochrysin SCHEMBL249043 | 0.81 | MAPT (1.00) | KDM4ECYP3A4MAPTALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110008-A1 | ANTI-ULCER ACTIVITY OF FLAVONE ANALOGS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-09-11 | — | — | WO | disclosed |