Sugi Predict

Sugi Predict / Compounds / SCHEMBL4051923

SCHEMBL4051923

SCHEMBL4051923

O=C(O)c1cc(/N=N/c2cccc([N+](=O)[O-])c2)ccc1O

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 6/20 0.77
▸ TDP1 Q9NUW8 3/20 0.77
▸ SMN1; SMN2 Q16637 2/20 0.77
▸ MEN1 O00255 6/20 0.64
▸ KMT2A Q03164 6/20 0.64
▸ PDE4A P27815 1/20 0.64
▸ BLVRB P30043 1/20 0.64
▸ KDR P35968 1/20 0.64
▸ HTT P42858 1/20 0.64
▸ GLO1 Q04760 2/20 0.58
▸ BLM P54132 2/20 0.57
▸ APP P05067 1/20 0.57
▸ THRB P10828 1/20 0.57
▸ RECQL P46063 1/20 0.57
▸ PHLPP2 Q6ZVD8 2/20 0.55
▸ CYP2C9 P11712 1/20 0.55
▸ PTGS1 P23219 1/20 0.55
▸ PTGS2 P35354 1/20 0.55
▸ HSD17B10 Q99714 1/20 0.55
▸ CYP2D6 P10635 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4047509 1.00 ALDH1A1 (0.77) ALDH1A1TDP1SMN1; SMN2MEN1KMT2A
SCHEMBL29481568 1.00 ALDH1A1 (0.77) ALDH1A1TDP1SMN1; SMN2MEN1KMT2A
SCHEMBL2384120 0.99 ALDH1A1 (0.75) ALDH1A1TDP1SMN1; SMN2MEN1KMT2A
SCHEMBL2384124 0.99 ALDH1A1 (0.75) ALDH1A1TDP1SMN1; SMN2MEN1KMT2A
SCHEMBL2384129 0.99 ALDH1A1 (0.75) ALDH1A1TDP1SMN1; SMN2MEN1KMT2A
SCHEMBL925266 0.88 ALDH1A1 (0.59) ALDH1A1TDP1SMN1; SMN2MEN1KMT2A
SCHEMBL2384122 0.88 ALDH1A1 (0.59) ALDH1A1TDP1SMN1; SMN2MEN1KMT2A
SCHEMBL29359461 0.87 TDP1 (1.00) ALDH1A1TDP1SMN1; SMN2MEN1KMT2A
SCHEMBL133646 0.87 TDP1 (1.00) ALDH1A1TDP1SMN1; SMN2MEN1KMT2A
SCHEMBL133647 0.87 TDP1 (1.00) ALDH1A1TDP1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108103582-A A kind of low-temp reversible thermochromic crystals material, preparation method and the usage 江南大学 2018-06-01 — — CN claimed
CN-102732055-A Multi-component chromogenic anion co-intercalation supramolecular structure pigment and preparation method thereof UNIV BEIJING CHEMICAL 2012-10-17 — — CN claimed
CN-1273550-C Aluminium salt bottoming acidic medium dye digitial printing ink and printing method of digital printing ink BEIJING GARMENT COLLEGE (CN) 2006-09-06 — — CN claimed
CN-1511896-A Aluminium salt bottoming acidic medium dye digitial printing ink and printing method of digital printing ink 北京服装学院 2004-07-14 — — CN claimed
EP-3366750-B1 STABILIZER AND STABILIZATION METHOD FUJIFILM WAKO PURE CHEMICAL CORP (JP) 2021-07-21 — — EP disclosed
US-10961185-B2 Stabilizer and stabilization method FUJIFILM WAKO PURE CHEMICAL CHEMICAL CORPORATION (JP) 2021-03-30 — — US disclosed
CN-107614156-B Copper powder and the manufacturing method for using its copper cream, conductive coating paint, conductive sheet and copper powder 住友金属矿山株式会社 2019-10-25 — — CN disclosed
CN-109589995-A A kind of catalyst and its application method of fast degradation Organic Pollutants in Wastewater 河北师范大学 2019-04-09 — — CN disclosed
US-20180290969-A1 STABILIZER AND STABILIZATION METHOD FUJIFILM WAKO PURE CHEMICAL CHEMICAL CORPORATION (JP) 2018-10-11 — — US disclosed
EP-3366750-A1 STABILIZER AND STABILIZATION METHOD FUJIFILM Wako Pure Chemical Corporation (JP) 2018-08-29 — — EP disclosed
CN-108103582-A A kind of low-temp reversible thermochromic crystals material, preparation method and the usage 江南大学 2018-06-01 — — CN disclosed
US-8735445-B2 Inhibitors of 15-hydroxyprostaglandin dehydrogenase for stimulating pigmentation of the skin or skin appendages L'OREAL (FR) 2014-05-27 — — US disclosed
US-6596469-B2 Using a heat sensitive coating of a polymer where aqueous developer solubility of the composition is not increased by incident UV radiation but is increased by delivery of heat KODAK POLYCHROME GRAPHICS, LLC 2003-07-22 — — US disclosed
US-20020136961-A1 Using a heat sensitive coating of a polymer where aqueous developer solubility of the composition is not increased by incident UV radiation but is increased by delivery of heat CITICORP NORTH AMERICA, INC., AS AGENT 2002-09-26 — — US disclosed
EP-0660699-B1 HAIR RELAXER COMPOSITIONS AMINCO INC (US) 2000-10-25 — — EP disclosed
US-5565216-A CREAM BASE CONTAINING WATER SOLUBLE SALT OF GUANIDINE WITH ANION CAPABLE OF BEING PRECIPITATED BY ALKALINE METAL ION, SECOND COMPONENT COMPRISING ALKALINE EARTH METAL OXIDE OR HYDROXIDE CARSON PRODUCTS COMPANY (US) 1996-10-15 — — US disclosed
EP-0660699-A4 HAIR RELAXER COMPOSITIONS. AMINCO INC (US) 1996-02-28 — — EP disclosed
EP-0660699-A1 HAIR RELAXER COMPOSITIONS AMINCO, INC. (US) 1995-07-05 — — EP disclosed
WO-1995003031-A1 HAIR RELAXER COMPOSITIONS AMINCO, INC. (US) 1995-02-02 — — WO disclosed
US-5145853-A Livestock infected with mycoplasma, salmonella, escherichia BAYER AKTIENGESELLSCHAFT (DE) 1992-09-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180290969-A1 STABILIZER AND STABILIZATION METHOD H1-0, H1-2, H1-4 ALDH1A1 993/4885TDP1 3455/4885SMN1; SMN2 278/4885
US-10961185-B2 Stabilizer and stabilization method H1-0, H1-2, H1-4 ALDH1A1 993/4885TDP1 3455/4885SMN1; SMN2 278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.