Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A known ✓ | P27815 | 1/20 | 0.62 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.56 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.53 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.75 |
| ▸ | MEN1 | O00255 | 6/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | BLVRB | P30043 | 1/20 | 0.62 |
| ▸ | KDR | P35968 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.56 |
| ▸ | BLM | P54132 | 2/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | PHLPP2 | Q6ZVD8 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29481568 | 0.99 | ALDH1A1 (0.77) | ALDH1A1TDP1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4051923 | 0.99 | ALDH1A1 (0.77) | ALDH1A1TDP1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4047509 | 0.99 | ALDH1A1 (0.77) | ALDH1A1TDP1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2384120 | 0.97 | ALDH1A1 (0.75) | ALDH1A1TDP1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2384124 | 0.97 | ALDH1A1 (0.75) | ALDH1A1TDP1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL925266 | 0.89 | ALDH1A1 (0.59) | ALDH1A1TDP1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2384122 | 0.89 | ALDH1A1 (0.59) | ALDH1A1TDP1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7033984 | 0.87 | TDP1 (0.97) | ALDH1A1TDP1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL29391739 | 0.86 | ALDH1A1 (0.56) | ALDH1A1TDP1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL133646 | 0.86 | TDP1 (1.00) | ALDH1A1TDP1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8026021-B2 | Film forming material and preparation of surface relief and optically anisotropic structures by irradiating a film of the said material | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2011-09-27 | — | — | US | disclosed |
| WO-2010021512-A2 | SILICA-BASED FLUORESCENT NANOPARTICLES | SNU R&DB FOUNDATION (KR) | 2010-02-25 | — | — | WO | disclosed |
| US-20100047859-A1 | SILICA-BASED FLUORESCENT NANOPARTICLES | SNU R&DB FOUNDATION (KR) | 2010-02-25 | — | — | US | disclosed |
| US-20090001632-A1 | Film Forming Material and Preparation of Surface Relief and Optically Anisotropic Structures by Irradiating a Film of the Said Material | FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) | 2009-01-01 | — | — | US | disclosed |
| EP-1794236-B1 | FILM FORMING MATERIAL AND PREPARATION OF SURFACE RELIEF AND OPTICALLY ANISOTROPIC STRUCTURES BY IRRADIATING A FILM OF THE SAID MATERIAL | FRAUNHOFER GES FORSCHUNG (DE) | 2008-12-31 | — | — | EP | disclosed |
| EP-1794236-A1 | FILM FORMING MATERIAL AND PREPARATION OF SURFACE RELIEF AND OPTICALLY ANISOTROPIC STRUCTURES BY IRRADIATING A FILM OF THE SAID MATERIAL | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2007-06-13 | — | — | EP | disclosed |
| WO-2006024500-A1 | FILM FORMING MATERIAL AND PREPARATION OF SURFACE RELIEF AND OPTICALLY ANISOTROPIC STRUCTURES BY IRRADIATING A FILM OF THE SAID MATERIAL | FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) | 2006-03-09 | — | — | WO | disclosed |
| EP-1632520-A1 | Film forming material and preparation of surface relief and optically anisotropic structures by irradiating a film of the said material | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2006-03-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100047859-A1 | SILICA-BASED FLUORESCENT NANOPARTICLES | NOXO1, NOX3, SOS1 | PDE4A 4875/4885THRB 4259/4885PTGS1 3869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.