SCHEMBL2384124

SCHEMBL2384124

O=C(O)c1cc(N=Nc2cccc([N+](=O)[O-])c2)ccc1O.[NaH]

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.75
TDP1 Q9NUW8 3/20 0.75
SMN1; SMN2 Q16637 2/20 0.75
MEN1 O00255 6/20 0.62
KMT2A Q03164 6/20 0.62
PDE4A P27815 1/20 0.62
BLVRB P30043 1/20 0.62
KDR P35968 1/20 0.62
HTT P42858 1/20 0.62
GLO1 Q04760 2/20 0.56
BLM P54132 2/20 0.56
APP P05067 1/20 0.56
THRB P10828 1/20 0.56
RECQL P46063 1/20 0.56
PHLPP2 Q6ZVD8 2/20 0.53
CYP2C9 P11712 1/20 0.53
PTGS1 P23219 1/20 0.53
PTGS2 P35354 1/20 0.53
HSD17B10 Q99714 1/20 0.53
MAPT P10636 4/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2384120 1.00 ALDH1A1 (0.75) ALDH1A1TDP1SMN1; SMN2MEN1KMT2A
SCHEMBL29481568 0.99 ALDH1A1 (0.77) ALDH1A1TDP1SMN1; SMN2MEN1KMT2A
SCHEMBL4051923 0.99 ALDH1A1 (0.77) ALDH1A1TDP1SMN1; SMN2MEN1KMT2A
SCHEMBL4047509 0.99 ALDH1A1 (0.77) ALDH1A1TDP1SMN1; SMN2MEN1KMT2A
SCHEMBL2384129 0.97 ALDH1A1 (0.75) ALDH1A1TDP1SMN1; SMN2MEN1KMT2A
SCHEMBL7033980 0.87 TDP1 (0.97) ALDH1A1TDP1SMN1; SMN2MEN1KMT2A
SCHEMBL7033973 0.87 TDP1 (0.97) ALDH1A1TDP1SMN1; SMN2MEN1KMT2A
SCHEMBL2384122 0.86 ALDH1A1 (0.59) ALDH1A1TDP1SMN1; SMN2MEN1KMT2A
SCHEMBL925266 0.86 ALDH1A1 (0.59) ALDH1A1TDP1SMN1; SMN2MEN1KMT2A
SCHEMBL133646 0.86 TDP1 (1.00) ALDH1A1TDP1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101031619-B Film-forming material and preparation of surface relief and optically anisotropic structures by irradiating a film of said material FRAUNHOFER GES FORSCHUNG 2012-04-11 CN disclosed
US-8026021-B2 Film forming material and preparation of surface relief and optically anisotropic structures by irradiating a film of the said material Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2011-09-27 US disclosed
WO-2010021512-A2 SILICA-BASED FLUORESCENT NANOPARTICLES SNU R&DB FOUNDATION (KR) 2010-02-25 WO disclosed
US-20100047859-A1 SILICA-BASED FLUORESCENT NANOPARTICLES SNU R&DB FOUNDATION (KR) 2010-02-25 US disclosed
US-20090001632-A1 Film Forming Material and Preparation of Surface Relief and Optically Anisotropic Structures by Irradiating a Film of the Said Material FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2009-01-01 US disclosed
EP-1794236-B1 FILM FORMING MATERIAL AND PREPARATION OF SURFACE RELIEF AND OPTICALLY ANISOTROPIC STRUCTURES BY IRRADIATING A FILM OF THE SAID MATERIAL FRAUNHOFER GES FORSCHUNG (DE) 2008-12-31 EP disclosed
CN-101031619-A Film-forming material and preparation of surface relief and optically anisotropic structures by irradiating a film of said material FRAUNHOFER GES FORSCHUNG (DE) 2007-09-05 CN disclosed
EP-1794236-A1 FILM FORMING MATERIAL AND PREPARATION OF SURFACE RELIEF AND OPTICALLY ANISOTROPIC STRUCTURES BY IRRADIATING A FILM OF THE SAID MATERIAL Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2007-06-13 EP disclosed
WO-2006024500-A1 FILM FORMING MATERIAL AND PREPARATION OF SURFACE RELIEF AND OPTICALLY ANISOTROPIC STRUCTURES BY IRRADIATING A FILM OF THE SAID MATERIAL FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 2006-03-09 WO disclosed
EP-1632520-A1 Film forming material and preparation of surface relief and optically anisotropic structures by irradiating a film of the said material Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2006-03-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100047859-A1 SILICA-BASED FLUORESCENT NANOPARTICLES NOXO1, NOX3, SOS1 ALDH1A1 1247/4885TDP1 4566/4885SMN1; SMN2 1118/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.