Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4401738 | 0.86 | CA12 (0.53) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL18024084 | 0.85 | KDM1A (0.46) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL3523671 | 0.81 | KDM1A (0.46) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL9557640 | 0.78 | CA12 (0.47) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL39800 | 0.78 | CA12 (0.47) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL16676932 | 0.78 | ALDH1A1 (0.54) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL8306308 | 0.78 | PAOX (0.51) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL3341356 | 0.77 | CA12 (0.50) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL15125105 | 0.77 | KDM1A (0.46) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL8309741 | 0.77 | ACE2 (0.72) | CA12CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2038264-A1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | F.HOFFMANN-LA ROCHE AG (CH) | 2009-03-25 | — | — | EP | disclosed |
| WO-2008000645-A1 | TETRAZOLE-SUBSTITUTED ARYLAMIDES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-01-03 | — | — | WO | disclosed |