SCHEMBL4052763

SCHEMBL4052763

Cc1cccc(Oc2ccc(O)cc2)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.67
LTA4H P09960 3/20 0.59
NR1H2 P55055 1/20 0.59
BAX Q07812 1/20 0.59
HTT P42858 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
L3MBTL1 Q9Y468 1/20 0.57
KMT2A Q03164 2/20 0.56
MEN1 O00255 1/20 0.56
ESR1 P03372 1/20 0.56
ESR2 Q92731 1/20 0.56
HSD17B1 P14061 1/20 0.53
HSD17B2 P37059 1/20 0.53
ACHE P22303 2/20 0.52
MAPK1 P28482 1/20 0.49
GFER P55789 1/20 0.49
AR P10275 1/20 0.49
GAA P10253 1/20 0.49
LMNA P02545 1/20 0.48
FFAR1 O14842 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30979254 1.00 ALDH1A1 (0.67) ALDH1A1LTA4HNR1H2BAXHTT
SCHEMBL10013917 0.89 ALDH1A1 (0.80) ALDH1A1HTTTDP1L3MBTL1KMT2A
SCHEMBL14159539 0.89 ALDH1A1 (0.80) ALDH1A1HTTTDP1L3MBTL1KMT2A
SCHEMBL23771947 0.88 HSD17B1 (0.58) ALDH1A1HTTTDP1L3MBTL1HSD17B1
SCHEMBL10016284 0.86 ESR1 (0.53) ALDH1A1LTA4HNR1H2BAXHTT
SCHEMBL30358261 0.86 ACHE (0.64) ALDH1A1HTTTDP1L3MBTL1KMT2A
SCHEMBL6061453 0.86 ACHE (0.64) ALDH1A1HTTTDP1L3MBTL1KMT2A
SCHEMBL822088 0.85 ALDH1A1 (0.74) ALDH1A1HTTTDP1L3MBTL1KMT2A
SCHEMBL822034 0.85 ALDH1A1 (0.74) ALDH1A1HTTTDP1L3MBTL1KMT2A
SCHEMBL30195024 0.85 ALDH1A1 (0.74) ALDH1A1HTTTDP1L3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240410055-A1 METHOD AND FORMULATION FOR PREPARING OPTICAL METAL OXIDE LAYERS MERCK PATENT GMBH (DE) 2024-12-12 US disclosed
CN-118076767-A Method and formulation for producing an optical metal oxide layer 默克专利有限公司 2024-05-24 CN disclosed
WO-2023057401-A1 METHOD AND FORMULATION FOR PREPARING OPTICAL METAL OXIDE LAYERS MERCK PATENT GMBH (DE) 2023-04-13 WO disclosed
US-9579325-B2 Modulators of TNF-α signaling GENZYME CORPORATION (US) 2017-02-28 US disclosed
CN-105102422-A Method for producing isocyanate ASAHI KASEI CHEMICALS CORP 2015-11-25 CN disclosed
EP-1481965-B1 AROMATIC AMINO ACID DERIVATIVES AND MEDICINAL COMPOSITIONS ENDO HITOSHI (JP) 2015-07-29 EP disclosed
EP-1380342-B1 COMPLEX CATALYST, PROCESS FOR PRODUCING THE COMPLEX CATALYST, AND PROCESS FOR PRODUCING ALCOHOL DERIVATIVE WITH THE COMPLEX CATALYST SUMITOMO CHEMICAL CO (JP) 2009-07-01 EP disclosed
US-7345068-B2 Aromatic amino acid derivatives and medicinal compositions Endou, Hitoshi (JP) 2008-03-18 US disclosed
US-7345068-B2 Aromatic amino acid derivatives and medicinal compositions Endou, Hitoshi (JP) 2008-03-18 US disclosed
CN-1281320-C Complex catalyst process for producing the complex catalyst and process for producing alcohol derivative with the complex catalyst SUMITOMO CHEMICAL CO (JP) 2006-10-25 CN disclosed
EP-0289919-A2 N-Substituted azoles BASF Aktiengesellschaft (DE) 1988-11-09 EP disclosed
US-4625048-A PESTICIDES HOFFMANN-LA ROCHE INC. (US) 1986-11-25 US disclosed
EP-0072475-B1 CARBAMIC ESTERS, PREPARATION THEREOF, PESTICIDAL COMPOSITIONS ON THE BASIS OF THESE COMPOUNDS AND THEIR USE IN COMBATING PESTS F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1986-08-20 EP disclosed
US-4607051-A Carbamic acid compound and use as a pesticide HOFFMANN-LA ROCHE INC. (US) 1986-08-19 US disclosed
US-4413010-A Carbamic acid esters and use as pesticides HOFFMANN-LA ROCHE INC. (US) 1983-11-01 US disclosed
EP-0072475-A2 Carbamic esters, preparation thereof, pesticidal compositions on the basis of these compounds and their use in combating pests F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1983-02-23 EP disclosed
EP-0004334-B1 CARBAMATES AND THEIR PESTICIDAL COMPOSITIONS, PREPARATIONS THEREOF AND USE THEREOF AS PESTICIDES F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1981-10-21 EP disclosed
US-4254262-A IN THE PRESENCE OF A QUATERNARY AMMONIUM OR PHOSPHONIUM SALT IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 1981-03-03 US disclosed
US-4215139-A PESTICIDES, INSECTICIDES HOFFMANN-LA ROCHE INC. (US) 1980-07-29 US disclosed
EP-0004334-A1 Carbamates and their pesticidal compositions, preparations thereof and use thereof as pesticides F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1979-10-03 EP disclosed