Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | PTPN7 | P35236 | 4/20 | 0.53 |
| ▸ | SELP | P16109 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17965716 | 1.00 | HMGCR (0.59) | HMGCRLMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL15283356 | 1.00 | HMGCR (0.59) | HMGCRLMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL5973668 | 0.95 | LMNA (0.62) | HMGCRLMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL415766 | 0.95 | LMNA (0.62) | HMGCRLMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL8924854 | 0.95 | LMNA (0.62) | HMGCRLMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL10397636 | 0.95 | LMNA (0.62) | HMGCRLMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL7057327 | 0.95 | LMNA (0.62) | HMGCRLMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL131748 | 0.95 | LMNA (0.62) | HMGCRLMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL5872593 | 0.95 | LMNA (0.62) | HMGCRLMNAALDH1A1HSD17B10MEN1 | |
| SCHEMBL4053328 | 0.93 | LMNA (0.59) | HMGCRLMNAALDH1A1HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2059496-A1 | ACETYLENIC COMPOUNDS | Commonwealth Scientific and Industrial Research Organisation (AU) | 2009-05-20 | — | — | EP | disclosed |
| WO-2008031157-A1 | ACETYLENIC COMPOUNDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2008-03-20 | — | — | WO | disclosed |
| WO-2008031157-A1 | ACETYLENIC COMPOUNDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2008-03-20 | — | — | WO | disclosed |