SCHEMBL7057327

SCHEMBL7057327

CCCCCCCCCCCC#CC#CCCCCO

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.62
ALDH1A1 P00352 2/20 0.62
HSD17B10 Q99714 1/20 0.62
MEN1 O00255 1/20 0.62
KMT2A Q03164 1/20 0.62
TSHR P16473 1/20 0.62
HMGCR P04035 4/20 0.59
PTPN7 P35236 4/20 0.59
SMN1; SMN2 Q16637 1/20 0.57
SELP P16109 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5872593 1.00 LMNA (0.62) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL5973668 1.00 LMNA (0.62) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL10397636 1.00 LMNA (0.62) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL8924854 1.00 LMNA (0.62) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL415766 1.00 LMNA (0.62) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL131748 1.00 LMNA (0.62) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL4053328 0.98 LMNA (0.59) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL17965716 0.95 HMGCR (0.59) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL15283356 0.95 HMGCR (0.59) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL4052897 0.95 HMGCR (0.59) LMNAALDH1A1HSD17B10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1113886-C Chemisorptive substance, aligned liquid-crystal film and liquid-crystal display element both made by using the same, and processes for producing these MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 2003-07-09 CN disclosed
US-20030104145-A1 Chemical adsorbent and liquid crystal alignment layer utilizing the same and liquid crystal display device utilizing the same and methods of manufacturing them MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2003-06-05 US disclosed
US-6495221-B1 EXTREMELY THIN AND TRANSPARENT FILM IN NANOMETER ORDER; HYDROCHALCONE DERIVATIVE SUBSTITUTED WITH A ISOCYANATOSILYL GROUP MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2002-12-17 US disclosed
EP-0962460-A1 CHEMISORPTIVE SUBSTANCE, ALIGNED LIQUID-CRYSTAL FILM AND LIQUID-CRYSTAL DISPLAY ELEMENT BOTH MADE BY USING THE SAME, AND PROCESSES FOR PRODUCING THESE MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1999-12-08 EP disclosed
CN-1236368-A Chemisorptive substance, aligned liquid-crystal film and liquid-crystal display element both made by using the same, and processes for producing these MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 1999-11-24 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030104145-A1 Chemical adsorbent and liquid crystal alignment layer utilizing the same and liquid crystal display device utilizing the same and methods of manufacturing them UACA, CRYAA, CUTA LMNA 2180/4885ALDH1A1 1972/4885HSD17B10 2987/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.