Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | HMGCR | P04035 | 4/20 | 0.59 |
| ▸ | PTPN7 | P35236 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | SELP | P16109 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5973668 | 1.00 | LMNA (0.62) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL10397636 | 1.00 | LMNA (0.62) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL8924854 | 1.00 | LMNA (0.62) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL7057327 | 1.00 | LMNA (0.62) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL415766 | 1.00 | LMNA (0.62) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL131748 | 1.00 | LMNA (0.62) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL4053328 | 0.98 | LMNA (0.59) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL17965716 | 0.95 | HMGCR (0.59) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL15283356 | 0.95 | HMGCR (0.59) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL4052897 | 0.95 | HMGCR (0.59) | LMNAALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7141437-B2 | Solid-state colorimetric biosensors comprised of dendritic polymer networks | MICHIGAN MOLECULAR INSTITUTE (US) | 2006-11-28 | — | — | US | disclosed |
| US-20050106572-A1 | star polymers comprising polyamidoamine having reactive end-groups, used for quantitative analysis | MICHIGAN MOLECULAR INSTITUTE | 2005-05-19 | — | — | US | disclosed |