Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 9/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3940815 | 0.70 | EGFR (0.34) | EGFR | |
| SCHEMBL80966 | 0.68 | EGFR (0.52) | EGFRPIK3CDPIK3CA | |
| SCHEMBL275923 | 0.68 | ALDH1A1 (0.46) | — | |
| SCHEMBL208208 | 0.67 | PARP1 (0.35) | — | |
| SCHEMBL6119198 | 0.67 | EGFR (0.50) | EGFRPIK3CDPIK3CA | |
| SCHEMBL3941104 | 0.67 | — | — | |
| SCHEMBL29865299 | 0.67 | EGFR (0.50) | EGFRPIK3CDPIK3CA | |
| SCHEMBL3627798 | 0.67 | — | — | |
| SCHEMBL211102 | 0.67 | DYRK1A (0.37) | — | |
| SCHEMBL209394 | 0.67 | HTR3A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2017264-A1 | Substituted phenyl propargyl compounds, method for their manufacture and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2009-01-21 | — | — | EP | disclosed |