Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10984145 | 0.90 | ALDH1A1 (0.66) | ALDH1A1RAB9ANPC1HPGDHTT | |
| SCHEMBL2585606 | 0.85 | ALDH1A1 (0.71) | ALDH1A1L3MBTL1RAB9ANPC1HPGD | |
| SCHEMBL12389676 | 0.83 | MAPT (0.62) | ALDH1A1L3MBTL1RAB9ANPC1HPGD | |
| SCHEMBL13838252 | 0.82 | MAPT (0.60) | ALDH1A1RAB9ANPC1HPGDHTT | |
| SCHEMBL6010241 | 0.80 | ALDH1A1 (1.00) | ALDH1A1RAB9ANPC1HPGDSMN1; SMN2 | |
| SCHEMBL24166921 | 0.80 | NPC1 (0.69) | ALDH1A1RAB9ANPC1HTTSMN1; SMN2 | |
| SCHEMBL13693551 | 0.79 | MAPT (0.62) | ALDH1A1L3MBTL1HPGDHTTSMN1; SMN2 | |
| SCHEMBL1880013 | 0.78 | RAB9A (0.57) | ALDH1A1L3MBTL1RAB9ANPC1HPGD | |
| SCHEMBL3633396 | 0.77 | NPC1 (0.84) | ALDH1A1RAB9ANPC1HTTSMN1; SMN2 | |
| SCHEMBL474757 | 0.77 | ALDH1A1 (0.70) | ALDH1A1L3MBTL1RAB9ANPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101129295-B | There is the binary initiator system of good storage stability and especially suitable for acidic system | HERAEUS KULZER GMBH (DE) | 2016-02-10 | — | — | CN | disclosed |
| WO-2009109998-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |
| CN-101129295-A | 2-component initiator system (amine free) with storage stability and especially suitable for acidic systems | HERAEUS KULZER GMBH (DE) | 2008-02-27 | — | — | CN | disclosed |
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |