SCHEMBL6010241

SCHEMBL6010241

CNC(=S)Nc1cccc(C(C)=O)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 1.00
NPC1 O15118 8/20 0.74
RAB9A P51151 7/20 0.74
SMN1; SMN2 Q16637 7/20 0.68
HPGD P15428 6/20 0.68
GAA P10253 4/20 0.68
ALOX12 P18054 2/20 0.68
KMT2A Q03164 3/20 0.66
MEN1 O00255 2/20 0.66
LMNA P02545 5/20 0.62
STAT1 P42224 1/20 0.62
MAPT P10636 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5456725 0.91 ALDH1A1 (0.83) ALDH1A1NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL7556866 0.88 ALDH1A1 (0.79) ALDH1A1NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL23455508 0.85 RAB9A (1.00) ALDH1A1NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL6816600 0.84 GAA (0.74) ALDH1A1NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL28879978 0.84 ALDH1A1 (0.72) ALDH1A1NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL14360821 0.83 ALDH1A1 (0.70) ALDH1A1NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL4371367 0.82 KMT2A (0.74) ALDH1A1NPC1RAB9ASMN1; SMN2GAA
SCHEMBL5457306 0.82 HPGD (0.74) ALDH1A1NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL1884508 0.81 ALDH1A1 (0.73) ALDH1A1NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL4053434 0.80 ALDH1A1 (0.71) ALDH1A1NPC1RAB9ASMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7022721-B1 Method and composition for rejuvenating cells, tissues, organs, hair and nails ULRICH PETER C 2006-04-04 US disclosed
EP-1368029-A4 METHOD AND COMPOSITION FOR REJUVINATING CELLS, TISSUES, ORGANS, HAIR AND NAILS FARRINGTON PHARMACEUTICALS LLC (US) 2006-02-15 EP disclosed
US-20050245512-A1 Method and composition for rejuvinating cells, tissues organs, hair and nails ULRICH PETER C 2005-11-03 US disclosed
US-6777557-B2 Method and composition for rejuvenating cells, tissues organs, hair and nails FARRINGTON PHARMACEUTICALS, LLC 2004-08-17 US disclosed
US-6689777-B2 DEPOLYMERIZING HEMOZOIN USING 2-IMINO-NAPHTHO(1,2-D)THIAZOL-5-OL DERIVATIVES KENNETH S. WARREN INSTITUTE 2004-02-10 US disclosed
EP-1368029-A2 METHOD AND COMPOSITION FOR REJUVINATING CELLS, TISSUES, ORGANS, HAIR AND NAILS Farrington Pharmaceuticals, LLC (US) 2003-12-10 EP disclosed
US-20030186993-A1 Anti-malarial compounds, compositions and methods KENNETH S. WARREN INSTITUTE 2003-10-02 US disclosed
US-20020188015-A1 Method and composition for rejuvinating cells, tissues organs, hair and nails FARRINGTON PHARMACEUTICALS, LLC 2002-12-12 US disclosed
WO-2002062301-A2 METHOD AND COMPOSITION FOR REJUVINATING CELLS, TISSUES, ORGANS, HAIR AND NAILS FARRINGTON PHARMACEUTICALS, LLC (US) 2002-08-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020188015-A1 Method and composition for rejuvinating cells, tissues organs, hair and nails TERT, TELO2, HKDC1 ALDH1A1 3396/4885NPC1 3338/4885RAB9A 1317/4885
US-20050245512-A1 Method and composition for rejuvinating cells, tissues organs, hair and nails TERT, TELO2, HKDC1 ALDH1A1 3396/4885NPC1 3338/4885RAB9A 1317/4885
US-20030186993-A1 Anti-malarial compounds, compositions and methods TYR, CRYZ, RHOT2 ALDH1A1 3325/4885NPC1 405/4885RAB9A 2037/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.