Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4050471 | 0.78 | PTGS2 (0.51) | MEN1KMT2APOLBBLMGPR35 | |
| SCHEMBL4050468 | 0.78 | PTGS2 (0.51) | MEN1KMT2APOLBBLMGPR35 | |
| SCHEMBL4058957 | 0.78 | HRH3 (0.57) | ALDH1A1MEN1KMT2ANPC1POLB | |
| SCHEMBL4052078 | 0.78 | HRH3 (0.57) | ALDH1A1MEN1KMT2ANPC1POLB | |
| SCHEMBL936767 | 0.77 | KMT2A (0.48) | ALDH1A1MEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL14125889 | 0.77 | MAPT (0.41) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL4052863 | 0.77 | MYC (0.46) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL4052867 | 0.77 | MYC (0.46) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL936476 | 0.77 | KMT2A (0.49) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL937188 | 0.77 | KMT2A (0.49) | ALDH1A1MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |