Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 1/20 | 0.58 |
| ▸ | MKNK1 | Q9BUB5 | 7/20 | 0.53 |
| ▸ | MKNK2 | Q9HBH9 | 6/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.49 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.49 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.46 |
| ▸ | NNMT | P40261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4061011 | 0.98 | MASP2 (0.56) | MASP2MKNK1MKNK2LTA4HSCN9A | |
| SCHEMBL4063091 | 0.81 | MASP2 (0.56) | MASP2SCN9ASCN3ACHEK2FYN | |
| Hydrochloric Acid SCHEMBL4058021 | 0.80 | MASP2 (0.54) | MASP2SCN9ASCN3ACHEK2FYN | |
| SCHEMBL28364786 | 0.79 | SCN9A (0.62) | MASP2LTA4HSCN9ASCN3A | |
| SCHEMBL18130901 | 0.78 | MASP2 (0.66) | MASP2LTA4HSCN9ARIPK1SCN3A | |
| SCHEMBL4053949 | 0.77 | MASP2 (0.70) | MASP2LTA4HSCN9ARIPK1SCN3A | |
| SCHEMBL20501048 | 0.77 | SCN9A (0.64) | MASP2LTA4HSCN9ASCN3A | |
| SCHEMBL4062253 | 0.76 | MASP2 (0.54) | MASP2LTA4HSCN9ASCN3ASMN1; SMN2 | |
| SCHEMBL4062250 | 0.76 | MASP2 (0.54) | MASP2LTA4HSCN9ASCN3ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4061012 | 0.76 | MASP2 (0.68) | MASP2LTA4HSCN9ARIPK1SCN3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9975857-B2 | Inhibition of bacterial biofilms with imidazole-phenyl derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2018-05-22 | — | — | US | disclosed |
| US-20150183746-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES | UNIV NORTH CAROLINA STATE (US) | 2015-07-02 | — | — | US | disclosed |
| US-9005643-B2 | Inhibition of bacterial biofilms with imidazole-phenyl derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-04-14 | — | — | US | disclosed |
| US-20090270475-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-29 | — | — | US | disclosed |
| WO-2009123753-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270475-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES | TFPI, O60361, PGLS | MASP2 774/4885MKNK1 660/4885MKNK2 676/4885 |
| US-20150183746-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES | TFPI, O60361, PGLS | MASP2 774/4885MKNK1 660/4885MKNK2 676/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.